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127 results

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Page 1
Neutralizing GDF-15 can overcome anti-PD-1 and anti-PD-L1 resistance in solid tumours.
Melero I, de Miguel Luken M, de Velasco G, Garralda E, Martín-Liberal J, Joerger M, Alonso G, Goebeler ME, Schuler M, König D, Dummer R, Reig M, Rodriguez Ruiz ME, Calvo E, Esteban-Villarrubia J, Oberoi A, Sabat P, Soto-Castillo JJ, Koster KL, Saavedra O, Sayehli C, Gromke T, Läubli H, Ramelyte E, Fortuny M, Landa-Magdalena A, Moreno I, Torres-Jiménez J, Hernando-Calvo A, Hess D, Racca F, Richly H, Schmitt AM, Eggenschwiler C, Sanduzzi-Zamparelli M, Vilalta-Lacarra A, Trojan J, Koch C, Galle PR, Foerster F, Trajanoski Z, Hackl H, Gogolla F, Koll FJ, Wild P, Chun FKH, Reis H, Lloyd P, Machacek M, Gajewski TF, Fridman WH, Eggermont AMM, Bargou R, Schöniger S, Rüschoff J, Tereshchenko A, Zink C, da Silva A, Lichtenegger FS, Akdemir J, Rüdiger M, L'Huillier P, Dutta A, Haake M, Auckenthaler A, Gjorgjioska A, Rössler B, Hermann F, Liebig M, Reichhardt D, Schuberth-Wagner C, Wischhusen J, Fettes P, Auer M, Klar K, Leo E. Melero I, et al. Among authors: wischhusen j. Nature. 2024 Dec 11. doi: 10.1038/s41586-024-08305-z. Online ahead of print. Nature. 2024. PMID: 39663448
Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene.
Gupta R, Dittmeier M, Wohlleben G, Nickl V, Bischler T, Luzak V, Wegat V, Doll D, Sodmann A, Bady E, Langlhofer G, Wachter B, Havlicek S, Gupta J, Horn E, Lüningschrör P, Villmann C, Polat B, Wischhusen J, Monoranu CM, Kuper J, Blum R. Gupta R, et al. Among authors: wischhusen j. Cancer Gene Ther. 2024 Sep;31(9):1357-1379. doi: 10.1038/s41417-024-00809-0. Epub 2024 Jul 22. Cancer Gene Ther. 2024. PMID: 39039193 Free PMC article.
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R, Wischhusen J. Haake M, et al. Among authors: wischhusen j. Nat Commun. 2023 Jul 20;14(1):4253. doi: 10.1038/s41467-023-39817-3. Nat Commun. 2023. PMID: 37474523 Free PMC article.
Defining characteristics and outcomes for patients with non-alcoholic fatty liver disease admitted to hospital with decompensated cirrhosis.
Trainee Collaborative for Research and Audit in Hepatology UK. Electronic address: [email protected]; Trainee Collaborative for Research and Audit in Hepatology UK. Trainee Collaborative for Research and Audit in Hepatology UK. Electronic address: [email protected], et al. J Hepatol. 2023 Oct;79(4):e165-e167. doi: 10.1016/j.jhep.2023.05.035. Epub 2023 Jun 12. J Hepatol. 2023. PMID: 37315808 No abstract available.
Regional variation in characteristics of patients with decompensated cirrhosis admitted to hospitals in the UK.
Trainee Collaborative for Research and Audit in Hepatology UK. Electronic address: [email protected]; Trainee Collaborative for Research and Audit in Hepatology UK. Trainee Collaborative for Research and Audit in Hepatology UK. Electronic address: [email protected], et al. Lancet Gastroenterol Hepatol. 2023 Jul;8(7):604-606. doi: 10.1016/S2468-1253(23)00114-0. Epub 2023 May 3. Lancet Gastroenterol Hepatol. 2023. PMID: 37148900 No abstract available.
127 results