Chen J - Search Results

1

Targeting viral suppressor of RNAi confers anti-coronaviral activity.

Chen J, Mu J, Zhou K, Zhang Y, Zhang J, Shu T, Shang W, Ren Y, Xu XQ, Zhang L, Yuan S, Zhang D, Cai K, Qiu Y, Zhou X. Chen J, et al. Mol Ther. 2025 Jan 8;33(1):201-214. doi: 10.1016/j.ymthe.2024.12.009. Epub 2024 Dec 10. Mol Ther. 2025. PMID: 39663700

2

Porcine Deltacoronavirus Infection Cleaves HDAC2 to Attenuate Its Antiviral Activity.

Li Z, Fang P, Duan P, Chen J, Fang L, Xiao S. Li Z, et al. Among authors: chen j. J Virol. 2022 Aug 24;96(16):e0102722. doi: 10.1128/jvi.01027-22. Epub 2022 Aug 2. J Virol. 2022. PMID: 35916536 Free PMC article.

3

Porcine Reproductive and Respiratory Syndrome Virus nsp11 Antagonizes Type I Interferon Signaling by Targeting IRF9.

Wang D, Chen J, Yu C, Zhu X, Xu S, Fang L, Xiao S. Wang D, et al. Among authors: chen j. J Virol. 2019 Jul 17;93(15):e00623-19. doi: 10.1128/JVI.00623-19. Print 2019 Aug 1. J Virol. 2019. PMID: 31092569 Free PMC article.

4

SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog.

Chen J, Li Z, Guo J, Xu S, Zhou J, Chen Q, Tong X, Wang D, Peng G, Fang L, Xiao S. Chen J, et al. Among authors: chen q. J Virol. 2022 Apr 27;96(8):e0003722. doi: 10.1128/jvi.00037-22. Epub 2022 Apr 7. J Virol. 2022. PMID: 35389264 Free PMC article.

5

Identification of novel proteolytically inactive mutations in coronavirus 3C-like protease using a combined approach.

Zhou J, Fang L, Yang Z, Xu S, Lv M, Sun Z, Chen J, Wang D, Gao J, Xiao S. Zhou J, et al. Among authors: chen j. FASEB J. 2019 Dec;33(12):14575-14587. doi: 10.1096/fj.201901624RR. Epub 2019 Nov 5. FASEB J. 2019. PMID: 31690127

In addition, our in-depth study of the dynamic substrate's envelope model using MD simulations is an approach that could augment the discovery of new inhibitors against 3CL(pro) in CoVs and other viral 3C proteases.-Zhou, J., Fang, L., Yang, Z., Xu, S., Lv, M., Sun, Z., …

In addition, our in-depth study of the dynamic substrate's envelope model using MD simulations is an approach that could augment the discove …

6

Assessing activity of Hepatitis A virus 3C protease using a cyclized luciferase-based biosensor.

Zhou J, Wang D, Xi Y, Zhu X, Yang Y, Lv M, Luo C, Chen J, Ye X, Fang L, Xiao S. Zhou J, et al. Among authors: chen j. Biochem Biophys Res Commun. 2017 Jul 8;488(4):621-627. doi: 10.1016/j.bbrc.2017.05.063. Epub 2017 May 10. Biochem Biophys Res Commun. 2017. PMID: 28501618 Free PMC article.

7

Porcine Deltacoronavirus nsp5 Cleaves DCP1A To Decrease Its Antiviral Activity.

Zhu X, Chen J, Tian L, Zhou Y, Xu S, Long S, Wang D, Fang L, Xiao S. Zhu X, et al. Among authors: chen j. J Virol. 2020 Jul 16;94(15):e02162-19. doi: 10.1128/JVI.02162-19. Print 2020 Jul 16. J Virol. 2020. PMID: 32461317 Free PMC article.

8

Evolutionary and genotypic analyses of global porcine epidemic diarrhea virus strains.

Guo J, Fang L, Ye X, Chen J, Xu S, Zhu X, Miao Y, Wang D, Xiao S. Guo J, et al. Among authors: chen j. Transbound Emerg Dis. 2019 Jan;66(1):111-118. doi: 10.1111/tbed.12991. Epub 2018 Aug 27. Transbound Emerg Dis. 2019. PMID: 30102851 Free PMC article.

9

Arterivirus nsp4 Antagonizes Interferon Beta Production by Proteolytically Cleaving NEMO at Multiple Sites.

Chen J, Wang D, Sun Z, Gao L, Zhu X, Guo J, Xu S, Fang L, Li K, Xiao S. Chen J, et al. J Virol. 2019 May 29;93(12):e00385-19. doi: 10.1128/JVI.00385-19. Print 2019 Jun 15. J Virol. 2019. PMID: 30944180 Free PMC article.

10

Tunable atomic spin-orbit coupling synthesized with a modulating gradient magnetic field.

Luo X, Wu L, Chen J, Guan Q, Gao K, Xu ZF, You L, Wang R. Luo X, et al. Among authors: chen j. Sci Rep. 2016 Jan 11;6:18983. doi: 10.1038/srep18983. Sci Rep. 2016. PMID: 26752786 Free PMC article.

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