Hedges CP - Search Results

1

An IL-6 promoter variant (-174 G/C) augments IL-6 production and alters skeletal muscle transcription in response to exercise in mice.

Watson LE, MacRae CL, Kallingappa P, Cao Y, Li X, Hedges CP, D'Souza RF, Fleming N, Mellor KM, Merry TL. Watson LE, et al. Among authors: hedges cp. J Appl Physiol (1985). 2025 Jan 1;138(1):213-225. doi: 10.1152/japplphysiol.00391.2024. Epub 2024 Dec 12. J Appl Physiol (1985). 2025. PMID: 39665197

2

Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men.

Hedges CP, Woodhead JST, Wang HW, Mitchell CJ, Cameron-Smith D, Hickey AJR, Merry TL. Hedges CP, et al. J Appl Physiol (1985). 2019 Feb 1;126(2):454-461. doi: 10.1152/japplphysiol.00777.2018. Epub 2018 Dec 20. J Appl Physiol (1985). 2019. PMID: 30571281 Free article.

3

High-intensity interval exercise increases humanin, a mitochondrial encoded peptide, in the plasma and muscle of men.

Woodhead JST, D'Souza RF, Hedges CP, Wan J, Berridge MV, Cameron-Smith D, Cohen P, Hickey AJR, Mitchell CJ, Merry TL. Woodhead JST, et al. Among authors: hedges cp. J Appl Physiol (1985). 2020 May 1;128(5):1346-1354. doi: 10.1152/japplphysiol.00032.2020. Epub 2020 Apr 9. J Appl Physiol (1985). 2020. PMID: 32271093 Free PMC article.

4

Deficiency in ROS-sensing nuclear factor erythroid 2-like 2 causes altered glucose and lipid homeostasis following exercise training.

Merry TL, MacRae C, Pham T, Hedges CP, Ristow M. Merry TL, et al. Among authors: hedges cp. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C337-C345. doi: 10.1152/ajpcell.00426.2019. Epub 2019 Nov 27. Am J Physiol Cell Physiol. 2020. PMID: 31774701 Free article.

5

α1-Antitrypsin A treatment attenuates neutrophil elastase accumulation and enhances insulin sensitivity in adipose tissue of mice fed a high-fat diet.

D'Souza RF, Masson SWC, Woodhead JST, James SL, MacRae C, Hedges CP, Merry TL. D'Souza RF, et al. Among authors: hedges cp. Am J Physiol Endocrinol Metab. 2021 Oct 1;321(4):E560-E570. doi: 10.1152/ajpendo.00181.2021. Epub 2021 Sep 6. Am J Physiol Endocrinol Metab. 2021. PMID: 34486403 Free article.

6

Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition.

D'Souza RF, Woodhead JST, Hedges CP, Zeng N, Wan J, Kumagai H, Lee C, Cohen P, Cameron-Smith D, Mitchell CJ, Merry TL. D'Souza RF, et al. Among authors: hedges cp. Aging (Albany NY). 2020 Mar 17;12(6):5244-5258. doi: 10.18632/aging.102944. Epub 2020 Mar 17. Aging (Albany NY). 2020. PMID: 32182209 Free PMC article.

7

Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice.

Hedges CP, Shetty B, Broome SC, MacRae C, Koutsifeli P, Buckels EJ, MacIndoe C, Boix J, Tsiloulis T, Matthews BG, Sinha S, Arendse M, Jaiswal JK, Mellor KM, Hickey AJR, Shepherd PR, Merry TL. Hedges CP, et al. Nat Aging. 2023 Feb;3(2):162-172. doi: 10.1038/s43587-022-00349-y. Epub 2023 Jan 23. Nat Aging. 2023. PMID: 37118113

8

A role for β-catenin in diet-induced skeletal muscle insulin resistance.

Masson SWC, Dissanayake WC, Broome SC, Hedges CP, Peeters WM, Gram M, Rowlands DS, Shepherd PR, Merry TL. Masson SWC, et al. Among authors: hedges cp. Physiol Rep. 2023 Feb;11(4):e15536. doi: 10.14814/phy2.15536. Physiol Rep. 2023. PMID: 36807886 Free PMC article.

9

Prolonged treatment with a PI3K p110α inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function.

Hedges CP, Pham T, Shetty B, Masson SWC, Hickey AJR, Shepherd PR, Merry TL. Hedges CP, et al. Biosci Rep. 2020 Oct 30;40(10):BSR20201128. doi: 10.1042/BSR20201128. Biosci Rep. 2020. PMID: 33006363 Free PMC article.

10

Minimal adaptation of the molecular regulators of mitochondrial dynamics in response to unilateral limb immobilisation and retraining in middle-aged men.

Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Zeng N, Figueiredo VC, Hickey AJR, Mitchell CJ, Cameron-Smith D. Pileggi CA, et al. Among authors: hedges cp. Eur J Appl Physiol. 2023 Feb;123(2):249-260. doi: 10.1007/s00421-022-05107-x. Epub 2022 Nov 30. Eur J Appl Physiol. 2023. PMID: 36449098

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