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Tumour extracellular vesicle-derived Complement Factor H promotes tumorigenesis and metastasis by inhibiting complement-dependent cytotoxicity of tumour cells.
Mao X, Zhou L, Tey SK, Ma APY, Yeung CLS, Ng TH, Wong SWK, Liu BHM, Fung YME, Patz EF Jr, Cao P, Gao Y, Yam JWP. Mao X, et al. Among authors: liu bhm. J Extracell Vesicles. 2020 Nov;10(1):e12031. doi: 10.1002/jev2.12031. Epub 2020 Nov 28. J Extracell Vesicles. 2020. PMID: 33708358 Free PMC article.
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Among authors: liu bhm. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics - An AI-Enabled Biological Target Discovery Platform.
Pun FW, Liu BHM, Long X, Leung HW, Leung GHD, Mewborne QT, Gao J, Shneyderman A, Ozerov IV, Wang J, Ren F, Aliper A, Bischof E, Izumchenko E, Guan X, Zhang K, Lu B, Rothstein JD, Cudkowicz ME, Zhavoronkov A. Pun FW, et al. Among authors: liu bhm. Front Aging Neurosci. 2022 Jun 28;14:914017. doi: 10.3389/fnagi.2022.914017. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35837482 Free PMC article.
Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine.
Pun FW, Leung GHD, Leung HW, Liu BHM, Long X, Ozerov IV, Wang J, Ren F, Aliper A, Izumchenko E, Moskalev A, de Magalhães JP, Zhavoronkov A. Pun FW, et al. Among authors: liu bhm. Aging (Albany NY). 2022 Mar 29;14(6):2475-2506. doi: 10.18632/aging.203960. Epub 2022 Mar 29. Aging (Albany NY). 2022. PMID: 35347083 Free PMC article.