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AI-powered therapeutic target discovery.
Pun FW, Ozerov IV, Zhavoronkov A. Pun FW, et al. Trends Pharmacol Sci. 2023 Sep;44(9):561-572. doi: 10.1016/j.tips.2023.06.010. Epub 2023 Jul 19. Trends Pharmacol Sci. 2023. PMID: 37479540 Free article. Review.
A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
Leveraging AI to identify dual-purpose aging and disease targets.
Leung GHD, Wong CW, Pun FW, Aliper A, Ren F, Zhavoronkov A. Leung GHD, et al. Among authors: pun fw. Expert Opin Ther Targets. 2024 Jun;28(6):473-476. doi: 10.1080/14728222.2023.2288270. Epub 2023 Dec 1. Expert Opin Ther Targets. 2024. PMID: 38038952 No abstract available.
PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery.
Kamya P, Ozerov IV, Pun FW, Tretina K, Fokina T, Chen S, Naumov V, Long X, Lin S, Korzinkin M, Polykovskiy D, Aliper A, Ren F, Zhavoronkov A. Kamya P, et al. Among authors: pun fw. J Chem Inf Model. 2024 May 27;64(10):3961-3969. doi: 10.1021/acs.jcim.3c01619. Epub 2024 Feb 25. J Chem Inf Model. 2024. PMID: 38404138 Free PMC article.
AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor.
Ren F, Ding X, Zheng M, Korzinkin M, Cai X, Zhu W, Mantsyzov A, Aliper A, Aladinskiy V, Cao Z, Kong S, Long X, Man Liu BH, Liu Y, Naumov V, Shneyderman A, Ozerov IV, Wang J, Pun FW, Polykovskiy DA, Sun C, Levitt M, Aspuru-Guzik A, Zhavoronkov A. Ren F, et al. Among authors: pun fw. Chem Sci. 2023 Jan 10;14(6):1443-1452. doi: 10.1039/d2sc05709c. eCollection 2023 Feb 8. Chem Sci. 2023. PMID: 36794205 Free PMC article.
TNIK's emerging role in cancer, metabolism, and age-related diseases.
Ewald CY, Pulous FE, Lok SWY, Pun FW, Aliper A, Ren F, Zhavoronkov A. Ewald CY, et al. Among authors: pun fw. Trends Pharmacol Sci. 2024 Jun;45(6):478-489. doi: 10.1016/j.tips.2024.04.010. Epub 2024 May 21. Trends Pharmacol Sci. 2024. PMID: 38777670 Free article. Review.
35 results