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Metabolic inhibition induces pyroptosis in uveal melanoma.
Varney SD, Erkes DA, Mersky GL, Mustafa MU, Chua V, Chervoneva I, Purwin TJ, Alnemri E, Aplin AE. Varney SD, et al. Among authors: aplin ae. Mol Cancer Res. 2024 Dec 13. doi: 10.1158/1541-7786.MCR-24-0508. Online ahead of print. Mol Cancer Res. 2024. PMID: 39670827
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death.
Rosenbaum SR, Caksa S, Stefanski CD, Trachtenberg IV, Wilson HP, Wilski NA, Ott CA, Purwin TJ, Haj JI, Pomante D, Kotas D, Chervoneva I, Capparelli C, Aplin AE. Rosenbaum SR, et al. Among authors: aplin ae. Mol Cancer Res. 2024 Feb 1;22(2):209-220. doi: 10.1158/1541-7786.MCR-23-0290. Mol Cancer Res. 2024. PMID: 37847239 Free PMC article.
Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma.
Chua V, Lapadula D, Randolph C, Benovic JL, Wedegaertner PB, Aplin AE. Chua V, et al. Among authors: aplin ae. Mol Cancer Res. 2017 May;15(5):501-506. doi: 10.1158/1541-7786.MCR-17-0007. Epub 2017 Feb 21. Mol Cancer Res. 2017. PMID: 28223438 Free PMC article. Review.
ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma.
Capparelli C, Purwin TJ, Heilman SA, Chervoneva I, McCue PA, Berger AC, Davies MA, Gershenwald JE, Krepler C, Aplin AE. Capparelli C, et al. Among authors: aplin ae. Cancer Res. 2018 Oct 1;78(19):5680-5693. doi: 10.1158/0008-5472.CAN-18-1001. Epub 2018 Aug 16. Cancer Res. 2018. PMID: 30115691 Free PMC article.
Effects of Oncogenic Gαq and Gα11 Inhibition by FR900359 in Uveal Melanoma.
Lapadula D, Farias E, Randolph CE, Purwin TJ, McGrath D, Charpentier TH, Zhang L, Wu S, Terai M, Sato T, Tall GG, Zhou N, Wedegaertner PB, Aplin AE, Aguirre-Ghiso J, Benovic JL. Lapadula D, et al. Among authors: aplin ae. Mol Cancer Res. 2019 Apr;17(4):963-973. doi: 10.1158/1541-7786.MCR-18-0574. Epub 2018 Dec 19. Mol Cancer Res. 2019. PMID: 30567972 Free PMC article.
163 results