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Design of Natterins-based peptides improves antimicrobial and antiviral activities.
de Cena GL, Tada DB, Lucchi DBM, Santos TAA, Heras M, Juliano M, Torres Braconi C, Castanho MARB, Lopes-Ferreira M, Conceição K. de Cena GL, et al. Among authors: castanho marb. Biotechnol Rep (Amst). 2024 Nov 28;45:e00867. doi: 10.1016/j.btre.2024.e00867. eCollection 2025 Mar. Biotechnol Rep (Amst). 2024. PMID: 39758971 Free PMC article.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Miranda HV, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Umemori J, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: castanho marb. Mol Ther. 2024 Dec 12:S1525-0016(24)00804-9. doi: 10.1016/j.ymthe.2024.12.005. Online ahead of print. Mol Ther. 2024. PMID: 39672159 No abstract available.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Vicente Miranda H, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: castanho marb. Mol Ther. 2024 Oct 2;32(10):3372-3401. doi: 10.1016/j.ymthe.2024.08.022. Epub 2024 Aug 27. Mol Ther. 2024. PMID: 39205389 Free article.
Repurposing anti-cancer porphyrin derivative drugs to target SARS-CoV-2 envelope.
Mendonça DA, Cadima-Couto I, Buga CC, Arnaut ZA, Schaberle FA, Arnaut LG, Castanho MARB, Cruz-Oliveira C. Mendonça DA, et al. Among authors: castanho marb. Biomed Pharmacother. 2024 Jul;176:116768. doi: 10.1016/j.biopha.2024.116768. Epub 2024 May 24. Biomed Pharmacother. 2024. PMID: 38795638 Free article.
Mechanistic insights on the antibacterial action of the kyotorphin peptide derivatives revealed by in vitro studies and Galleria mellonella proteomic analysis.
de Andrade VM, de Oliveira VDM, Barcick U, Ramu VG, Heras M, Bardají ER, Castanho MARB, Zelanis A, Capella A, Junqueira JC, Conceição K. de Andrade VM, et al. Among authors: castanho marb. Microb Pathog. 2024 Apr;189:106607. doi: 10.1016/j.micpath.2024.106607. Epub 2024 Mar 2. Microb Pathog. 2024. PMID: 38437995
Quantitative Imaging of the Action of vCPP2319, an Antimicrobial Peptide from a Viral Scaffold, against Staphylococcus aureus Biofilms of a Clinical Isolate.
Dias SA, Pinto SN, Silva-Herdade AS, Cavaco M, Neves V, Tavares L, Oliveira M, Andreu D, Coutinho A, Castanho MARB, Veiga AS. Dias SA, et al. Among authors: castanho marb. ACS Infect Dis. 2023 Oct 13;9(10):1889-1900. doi: 10.1021/acsinfecdis.3c00195. Epub 2023 Sep 5. ACS Infect Dis. 2023. PMID: 37669146 Free PMC article.
173 results