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Store-operated Ca 2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells.
Babicheva A, Elmadbouh I, Song S, Thompson M, Powers R, Jain PP, Izadi A, Chen J, Yung L, Parmisano S, Paquin C, Wang WT, Chen Y, Wang T, Alotaibi M, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Prakash YS, Pabelick CM, Yuan JX. Babicheva A, et al. Among authors: jain pp. bioRxiv [Preprint]. 2024 Dec 8:2024.12.06.627034. doi: 10.1101/2024.12.06.627034. bioRxiv. 2024. PMID: 39677696 Free PMC article. Preprint.
Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.
Rodriguez M, Chen J, Jain PP, Babicheva A, Xiong M, Li J, Lai N, Zhao T, Hernandez M, Balistrieri A, Parmisano S, Simonson T, Breen E, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Rodriguez M, et al. Among authors: jain pp. Front Physiol. 2021 Aug 2;12:714785. doi: 10.3389/fphys.2021.714785. eCollection 2021. Front Physiol. 2021. PMID: 34408668 Free PMC article.
TRPC6, a therapeutic target for pulmonary hypertension.
Jain PP, Lai N, Xiong M, Chen J, Babicheva A, Zhao T, Parmisano S, Zhao M, Paquin C, Matti M, Powers R, Balistrieri A, Kim NH, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Garcia JGN, Makino A, Yuan JX. Jain PP, et al. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;321(6):L1161-L1182. doi: 10.1152/ajplung.00159.2021. Epub 2021 Oct 27. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34704831 Free PMC article.
Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation.
Chen J, Rodriguez M, Miao J, Liao J, Jain PP, Zhao M, Zhao T, Babicheva A, Wang Z, Parmisano S, Powers R, Matti M, Paquin C, Soroureddin Z, Shyy JY, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Chen J, et al. Among authors: jain pp. Am J Physiol Lung Cell Mol Physiol. 2022 May 1;322(5):L737-L760. doi: 10.1152/ajplung.00447.2021. Epub 2022 Mar 23. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35318857 Free PMC article.
Mouse model of experimental pulmonary hypertension: Lung angiogram and right heart catheterization.
Xiong M, Jain PP, Chen J, Babicheva A, Zhao T, Alotaibi M, Kim NH, Lai N, Izadi A, Rodriguez M, Li J, Balistrieri A, Balistrieri F, Parmisano S, Sun X, Voldez-Jasso D, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Xiong M, et al. Among authors: jain pp. Pulm Circ. 2021 Sep 8;11(4):20458940211041512. doi: 10.1177/20458940211041512. eCollection 2021 Oct-Dec. Pulm Circ. 2021. PMID: 34531976 Free PMC article.
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension.
Wang Z, Chen J, Babicheva A, Jain PP, Rodriguez M, Ayon RJ, Ravellette KS, Wu L, Balistrieri F, Tang H, Wu X, Zhao T, Black SM, Desai AA, Garcia JGN, Sun X, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Wang J, Yuan JX. Wang Z, et al. Among authors: jain pp. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1010-C1027. doi: 10.1152/ajpcell.00147.2021. Epub 2021 Oct 20. Am J Physiol Cell Physiol. 2021. PMID: 34669509 Free PMC article.
Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung.
Jain PP, Hosokawa S, Xiong M, Babicheva A, Zhao T, Rodriguez M, Rahimi S, Pourhashemi K, Balistrieri F, Lai N, Malhotra A, Shyy JY, Valdez-Jasso D, Thistlethwaite PA, Makino A, Yuan JX. Jain PP, et al. Pulm Circ. 2020 Nov 25;10(4):2045894020956592. doi: 10.1177/2045894020956592. eCollection 2020 Oct-Dec. Pulm Circ. 2020. PMID: 33282184 Free PMC article.
Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension.
Wu K, Tang H, Lin R, Carr SG, Wang Z, Babicheva A, Ayon RJ, Jain PP, Xiong M, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Valdez-Jasso D, Simonson TS, Desai AA, Garcia JGN, Shyy JY, Thistlethwaite PA, Wang J, Makino A, Yuan JX. Wu K, et al. Among authors: jain pp. Pulm Circ. 2020 Sep 10;10(3):2045894020948470. doi: 10.1177/2045894020948470. eCollection 2020 Jul-Sep. Pulm Circ. 2020. PMID: 33294172 Free PMC article.
Halofuginone, a promising drug for treatment of pulmonary hypertension.
Jain PP, Zhao T, Xiong M, Song S, Lai N, Zheng Q, Chen J, Carr SG, Babicheva A, Izadi A, Rodriguez M, Rahimi S, Balistrieri F, Rahimi S, Simonson T, Valdez-Jasso D, Thistlethwaite PA, Shyy JY, Wang J, Makino A, Yuan JX. Jain PP, et al. Br J Pharmacol. 2021 Sep;178(17):3373-3394. doi: 10.1111/bph.15442. Epub 2021 Jul 31. Br J Pharmacol. 2021. PMID: 33694155 Free PMC article.
32 results