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Structural Convergence and Water-Mediated Substrate Mimicry Enable Broad Neuraminidase Inhibition by Human Antibodies.
Lederhofer J, Borst AJ, Nguyen L, Gillespie RA, Williams CJ, Walker EL, Raab JE, Yap C, Ellis D, Creanga A, Tan HX, Do THT, Ravichandran M, McDermott AB, Sage VL, Andrews SF, Graham BS, Wheatley AK, Reed DS, King NP, Kanekiyo M. Lederhofer J, et al. Among authors: wheatley ak. bioRxiv [Preprint]. 2024 Dec 3:2024.11.27.625426. doi: 10.1101/2024.11.27.625426. bioRxiv. 2024. PMID: 39677750 Free PMC article. Preprint.
Blood Distribution of SARS-CoV-2 Lipid Nanoparticle mRNA Vaccine in Humans.
Kent SJ, Li S, Amarasena TH, Reynaldi A, Lee WS, Leeming MG, O'Connor DH, Nguyen J, Kent HE, Caruso F, Juno JA, Wheatley AK, Davenport MP, Ju Y. Kent SJ, et al. Among authors: wheatley ak. ACS Nano. 2024 Oct 1;18(39):27077-27089. doi: 10.1021/acsnano.4c11652. Epub 2024 Sep 19. ACS Nano. 2024. PMID: 39298422 Free PMC article.
SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.
Rowntree LC, Audsley J, Allen LF, McQuilten HA, Hagen RR, Chaurasia P, Petersen J, Littler DR, Tan HX, Murdiyarso L, Habel JR, Foo IJH, Zhang W, Ten Berge ERV, Ganesh H, Kaewpreedee P, Lee KWK, Cheng SMS, Kwok JSY, Jayasinghe D, Gras S, Juno JA, Wheatley AK, Kent SJ, Rossjohn J, Cheng AC, Kotsimbos TC, Trubiano JA, Holmes NE, Pang Chan KK, Hui DSC, Peiris M, Poon LLM, Lewin SR, Doherty PC, Thevarajan I, Valkenburg SA, Kedzierska K, Nguyen THO. Rowntree LC, et al. Among authors: wheatley ak. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411428121. doi: 10.1073/pnas.2411428121. Epub 2024 Sep 16. Proc Natl Acad Sci U S A. 2024. PMID: 39284068 Free PMC article.
Randomized controlled trial reveals no benefit to a 3-month delay in COVID-19 mRNA booster vaccine.
Lee WS, Audsley J, Trieu MC, Reynaldi A, Aurelia LC, Mehta PH, Patterson J, Kent HE, Nguyen J, Amarasena T, Esterbauer R, Haycroft ER, Ramanathan P, Davenport MP, Schlub TE, Sasadeusz J, Wheatley AK, Chung AW, Juno JA, Selva KJ, Kent SJ. Lee WS, et al. Among authors: wheatley ak. J Clin Invest. 2024 Jul 11;134(17):e181244. doi: 10.1172/JCI181244. J Clin Invest. 2024. PMID: 38990644 Free PMC article. Clinical Trial.
Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents.
Purcell RA, Aurelia LC, Esterbauer R, Allen LF, Bond KA, Williamson DA, Trevillyan JM, Trubiano JA, Juno JJ, Wheatley AK, Davenport MP, Nguyen TH, Kedzierska K, Kent SJ, Selva KJ, Chung AW. Purcell RA, et al. Among authors: wheatley ak. Clin Transl Immunology. 2024 Feb 29;13(3):e1494. doi: 10.1002/cti2.1494. eCollection 2024. Clin Transl Immunology. 2024. PMID: 38433763 Free PMC article.
135 results