Murphy JM - Search Results

1

FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-Cbl-NF-κB signaling.

Murphy JM, Tran DTK, Jeong K, Nguyen L, Nguyen MT, Tambe D, Jo H, Ahn EE, Lim SS. Murphy JM, et al. bioRxiv [Preprint]. 2024 Dec 8:2024.12.06.627217. doi: 10.1101/2024.12.06.627217. bioRxiv. 2024. PMID: 39677751 Free PMC article. Preprint.

2

FAK inhibition suppresses breast cancer progression via DNA methylation-mediated DAB2 gene reactivation.

Murphy JM, Jeong K, Ahn EE, Lim SS. Murphy JM, et al. bioRxiv [Preprint]. 2024 Nov 25:2024.11.23.624992. doi: 10.1101/2024.11.23.624992. bioRxiv. 2024. PMID: 39651254 Free PMC article. Preprint.

3

Nuclear FAK in endothelium: An intrinsic inhibitor of NF-κB activation in atherosclerosis.

Murphy JM, Jeong K, Tran DTK, Cioffi DL, Campbell PM, Kim JH, Jo H, Ahn EE, Lim SS. Murphy JM, et al. Atherosclerosis. 2023 Aug;379:117189. doi: 10.1016/j.atherosclerosis.2023.117189. Epub 2023 Jul 26. Atherosclerosis. 2023. PMID: 37527611 Free PMC article.

4

A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis.

Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: murphy jm. bioRxiv [Preprint]. 2023 Nov 19:2023.11.19.567732. doi: 10.1101/2023.11.19.567732. bioRxiv. 2023. Update in: JCI Insight. 2024 Mar 8;9(5):e175053. doi: 10.1172/jci.insight.175053 PMID: 38014320 Free PMC article. Updated. Preprint.

5

FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.

Murphy JM, Jeong K, Rodriguez YAR, Kim JH, Ahn EE, Lim SS. Murphy JM, et al. Sci Rep. 2019 May 20;9(1):7617. doi: 10.1038/s41598-019-44098-2. Sci Rep. 2019. PMID: 31110200 Free PMC article.

6

FAK Family Kinases in Vascular Diseases.

Murphy JM, Jeong K, Lim SS. Murphy JM, et al. Int J Mol Sci. 2020 May 21;21(10):3630. doi: 10.3390/ijms21103630. Int J Mol Sci. 2020. PMID: 32455571 Free PMC article. Review.

7

FAK in the nucleus prevents VSMC proliferation by promoting p27 and p21 expression via Skp2 degradation.

Jeong K, Murphy JM, Ahn EE, Lim SS. Jeong K, et al. Among authors: murphy jm. Cardiovasc Res. 2022 Mar 16;118(4):1150-1163. doi: 10.1093/cvr/cvab132. Cardiovasc Res. 2022. PMID: 33839758 Free PMC article.

8

FAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expression.

Jeong K, Murphy JM, Rodriguez YAR, Kim JS, Ahn EE, Lim SS. Jeong K, et al. Among authors: murphy jm. Biochem Biophys Res Commun. 2019 Feb 19;509(4):1034-1040. doi: 10.1016/j.bbrc.2019.01.050. Epub 2019 Jan 17. Biochem Biophys Res Commun. 2019. PMID: 30660359 Free PMC article.

9

Targeting focal adhesion kinase in cancer cells and the tumor microenvironment.

Murphy JM, Rodriguez YAR, Jeong K, Ahn EE, Lim SS. Murphy JM, et al. Exp Mol Med. 2020 Jun;52(6):877-886. doi: 10.1038/s12276-020-0447-4. Epub 2020 Jun 9. Exp Mol Med. 2020. PMID: 32514188 Free PMC article. Review.

10

Focal Adhesion Kinase Activity and Localization is Critical for TNF-α-Induced Nuclear Factor-κB Activation.

Murphy JM, Jeong K, Cioffi DL, Campbell PM, Jo H, Ahn EE, Lim SS. Murphy JM, et al. Inflammation. 2021 Jun;44(3):1130-1144. doi: 10.1007/s10753-020-01408-5. Epub 2021 Feb 2. Inflammation. 2021. PMID: 33527321 Free PMC article.

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