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The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation.
Immler R, Nadolni W, Bertsch A, Morikis V, Rohwedder I, Masgrau-Alsina S, Schroll T, Yevtushenko A, Soehnlein O, Moser M, Gudermann T, Barnea ER, Rehberg M, Simon SI, Zierler S, Pruenster M, Sperandio M. Immler R, et al. Among authors: sperandio m. Cardiovasc Res. 2022 Mar 25;118(5):1289-1302. doi: 10.1093/cvr/cvab133. Cardiovasc Res. 2022. PMID: 33881519 Free PMC article.
Neonatal neutrophils exhibit reduced NLRP3 inflammasome activation.
Wackerbarth LM, Seifert SB, Napoli M, Rohwedder I, Vogl T, Scheiermann C, Kolben T, Nussbaum C, Pruenster M, Immler R, Sperandio M. Wackerbarth LM, et al. Among authors: sperandio m. J Leukoc Biol. 2024 Sep 23:qiae206. doi: 10.1093/jleuko/qiae206. Online ahead of print. J Leukoc Biol. 2024. PMID: 39312228
The eATP/P2×7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation.
Li C, Liu Q, Han L, Zhang H, Immler R, Rathkolb B, Secklehner J, de Angelis MH, Yildirim AÖ, Zeuschner D, Nicke A, Carlin LM, Sperandio M, Stoeger T, Rehberg M. Li C, et al. Among authors: sperandio m. Adv Sci (Weinh). 2024 Dec;11(45):e2404661. doi: 10.1002/advs.202404661. Epub 2024 Oct 4. Adv Sci (Weinh). 2024. PMID: 39364760 Free PMC article.
Antibodies and complement are key drivers of thrombosis.
Stark K, Kilani B, Stockhausen S, Busse J, Schubert I, Tran TD, Gaertner F, Leunig A, Pekayvaz K, Nicolai L, Fumagalli V, Stermann J, Stephan F, David C, Müller MB, Heyman B, Lux A, da Palma Guerreiro A, Frenzel LP, Schmidt CQ, Dopler A, Moser M, Chandraratne S, von Brühl ML, Lorenz M, Korff T, Rudelius M, Popp O, Kirchner M, Mertins P, Nimmerjahn F, Iannacone M, Sperandio M, Engelmann B, Verschoor A, Massberg S. Stark K, et al. Among authors: sperandio m. Immunity. 2024 Sep 10;57(9):2140-2156.e10. doi: 10.1016/j.immuni.2024.08.007. Epub 2024 Sep 2. Immunity. 2024. PMID: 39226900 Free article.
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.
Wang M, Flaswinkel H, Joshi A, Napoli M, Masgrau-Alsina S, Kamper JM, Henne A, Heinz A, Berouti M, Schmacke NA, Hiller K, Kremmer E, Wefers B, Wurst W, Sperandio M, Ruland J, Fröhlich T, Hornung V. Wang M, et al. Among authors: sperandio m. Nat Commun. 2024 Jul 31;15(1):6438. doi: 10.1038/s41467-024-50104-7. Nat Commun. 2024. PMID: 39085210 Free PMC article.
CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.
Immler R, Nussbaumer K, Doerner A, El Bounkari O, Huber S, Abisch J, Napoli M, Schmidt S, Margraf A, Pruenster M, Rohwedder I, Lange-Sperandio B, Mall MA, de Jong R, Ohnmacht C, Bernhagen J, Voehringer D, Marth JD, Frommhold D, Sperandio M. Immler R, et al. Among authors: sperandio m. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2319057121. doi: 10.1073/pnas.2319057121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687790 Free PMC article.
286 results