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Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients.
Randolph HE, Aguirre-Gamboa R, Brunet-Ratnasingham E, Nakanishi T, Locher V, Ketter E, Brandolino C, Larochelle C, Prat A, Arbour N, Dumaine A, Finzi A, Durand M, Richards JB, Kaufmann DE, Barreiro LB. Randolph HE, et al. Among authors: prat a. bioRxiv [Preprint]. 2024 Dec 4:2024.12.03.626676. doi: 10.1101/2024.12.03.626676. bioRxiv. 2024. PMID: 39677792 Free PMC article. Preprint.
Identification of SARS-CoV-2-specific immune alterations in acutely ill patients.
Rébillard RM, Charabati M, Grasmuck C, Filali-Mouhim A, Tastet O, Brassard N, Daigneault A, Bourbonnière L, Anand SP, Balthazard R, Beaudoin-Bussières G, Gasser R, Benlarbi M, Moratalla AC, Solorio YC, Boutin M, Farzam-Kia N, Descôteaux-Dinelle J, Fournier AP, Gowing E, Laumaea A, Jamann H, Lahav B, Goyette G, Lemaître F, Mamane VH, Prévost J, Richard J, Thai K, Cailhier JF, Chomont N, Finzi A, Chassé M, Durand M, Arbour N, Kaufmann DE, Prat A, Larochelle C. Rébillard RM, et al. Among authors: prat a. J Clin Invest. 2021 Apr 15;131(8):e145853. doi: 10.1172/JCI145853. J Clin Invest. 2021. PMID: 33635833 Free PMC article.
Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality.
Brunet-Ratnasingham E, Anand SP, Gantner P, Dyachenko A, Moquin-Beaudry G, Brassard N, Beaudoin-Bussières G, Pagliuzza A, Gasser R, Benlarbi M, Point F, Prévost J, Laumaea A, Niessl J, Nayrac M, Sannier G, Orban C, Messier-Peet M, Butler-Laporte G, Morrison DR, Zhou S, Nakanishi T, Boutin M, Descôteaux-Dinelle J, Gendron-Lepage G, Goyette G, Bourassa C, Medjahed H, Laurent L, Rébillard RM, Richard J, Dubé M, Fromentin R, Arbour N, Prat A, Larochelle C, Durand M, Richards JB, Chassé M, Tétreault M, Chomont N, Finzi A, Kaufmann DE. Brunet-Ratnasingham E, et al. Among authors: prat a. Sci Adv. 2021 Nov 26;7(48):eabj5629. doi: 10.1126/sciadv.abj5629. Epub 2021 Nov 26. Sci Adv. 2021. PMID: 34826237 Free PMC article.
Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity.
Brunet-Ratnasingham E, Morin S, Randolph HE, Labrecque M, Bélair J, Lima-Barbosa R, Pagliuzza A, Marchitto L, Hultström M, Niessl J, Cloutier R, Sreng Flores AM, Brassard N, Benlarbi M, Prévost J, Ding S, Anand SP, Sannier G, Marks A, Wågsäter D, Bareke E, Zeberg H, Lipcsey M, Frithiof R, Larsson A, Zhou S, Nakanishi T, Morrison D, Vezina D, Bourassa C, Gendron-Lepage G, Medjahed H, Point F, Richard J, Larochelle C, Prat A, Cunningham JL, Arbour N, Durand M, Richards JB, Moon K, Chomont N, Finzi A, Tétreault M, Barreiro L, Wolf G, Kaufmann DE. Brunet-Ratnasingham E, et al. Among authors: prat a. Nat Commun. 2024 May 16;15(1):4177. doi: 10.1038/s41467-024-48556-y. Nat Commun. 2024. PMID: 38755196 Free PMC article.
Update on treatments in multiple sclerosis.
Michel L, Larochelle C, Prat A. Michel L, et al. Among authors: prat a. Presse Med. 2015 Apr;44(4 Pt 2):e137-51. doi: 10.1016/j.lpm.2015.02.008. Epub 2015 Mar 23. Presse Med. 2015. PMID: 25813102 Review.
Interleukin-15 enhances proinflammatory T-cell responses in patients with MS and EAE.
Laurent C, Deblois G, Clénet ML, Carmena Moratalla A, Farzam-Kia N, Girard M, Duquette P, Prat A, Larochelle C, Arbour N. Laurent C, et al. Among authors: prat a. Neurol Neuroimmunol Neuroinflamm. 2020 Dec 15;8(1):e931. doi: 10.1212/NXI.0000000000000931. Print 2021 Jan. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 33323466 Free PMC article.
Single-Cell Transcriptomics Identifies Brain Endothelium Inflammatory Networks in Experimental Autoimmune Encephalomyelitis.
Fournier AP, Tastet O, Charabati M, Hoornaert C, Bourbonnière L, Klement W, Larouche S, Tea F, Wang YC, Larochelle C, Arbour N, Ragoussis J, Zandee S, Prat A. Fournier AP, et al. Among authors: prat a. Neurol Neuroimmunol Neuroinflamm. 2022 Nov 29;10(1):e200046. doi: 10.1212/NXI.0000000000200046. Print 2023 Jan. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 36446612 Free PMC article.
951 results