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Page 1
Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors.
Bazua-Valenti S, Brown MR, Zavras J, Riedl Khursigara M, Grinkevich E, Sidhom EH, Keller KH, Racette M, Dvela-Levitt M, Quintanova C, Demirci H, Sewerin S, Goss AC, Lin J, Yoo H, Vaca Jacome AS, Papanastasiou M, Udeshi N, Carr SA, Himmerkus N, Bleich M, Mutig K, Bachmann S, Halbritter J, Kmoch S, Živná M, Kidd K, Bleyer AJ, Weins A, Alper SL, Shaw JL, Kost-Alimova M, Pablo JLB, Greka A. Bazua-Valenti S, et al. Among authors: papanastasiou m. J Clin Invest. 2024 Dec 16;134(24):e180347. doi: 10.1172/JCI180347. J Clin Invest. 2024. PMID: 39680459 Free PMC article.
Chemical perturbations impacting histone acetylation govern colorectal cancer differentiation.
Likasitwatanakul P, Li Z, Doan P, Spisak S, Raghawan AK, Liu Q, Liow P, Lee S, Chen D, Bala P, Sahgal P, Aitymbayev D, Thalappillil JS, Papanastasiou M, Hawkins W, Carr SA, Park H, Cleary JM, Qi J, Sethi NS. Likasitwatanakul P, et al. Among authors: papanastasiou m. bioRxiv [Preprint]. 2024 Dec 10:2024.12.06.626451. doi: 10.1101/2024.12.06.626451. bioRxiv. 2024. PMID: 39713466 Free PMC article. Preprint.
ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer.
DiCiaccio B, Seehawer M, Li Z, Patmanidis A, Bui T, Foidart P, Nishida J, D'Santos CS, Papachristou EK, Papanastasiou M, Reiter AH, Qiu X, Li R, Jiang Y, Huang XY, Simeonov A, Kales SC, Rai G, Lal-Nag M, Jadhav A, Brown M, Carroll JS, Long HW, Polyak K. DiCiaccio B, et al. Among authors: papanastasiou m. Cell Rep. 2024 Dec 24;43(12):114991. doi: 10.1016/j.celrep.2024.114991. Epub 2024 Nov 20. Cell Rep. 2024. PMID: 39570746 Free PMC article.
Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors.
Camarda ND, Lu Q, Meola DM, Man JJ, Song Z, Travers RJ, Lopez KE, Powers SN, Papanastasiou M, DeRuff KC, Mullahoo J, Egri SB, Davison D, Sebastiani P, Eblen ST, Buchsbaum R, Huggins GS, London CA, Jaffe JD, Upshaw JN, Yang VK, Jaffe IZ. Camarda ND, et al. Among authors: papanastasiou m. Clin Sci (Lond). 2024 Sep 18;138(18):1131-1150. doi: 10.1042/CS20240537. Clin Sci (Lond). 2024. PMID: 39282930
Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3.
Seehawer M, Li Z, Nishida J, Foidart P, Reiter AH, Rojas-Jimenez E, Goyette MA, Yan P, Raval S, Munoz Gomez M, Cejas P, Long HW, Papanastasiou M, Polyak K. Seehawer M, et al. Among authors: papanastasiou m. Nat Cell Biol. 2024 Jul;26(7):1165-1175. doi: 10.1038/s41556-024-01446-3. Epub 2024 Jun 26. Nat Cell Biol. 2024. PMID: 38926506 Free PMC article.
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.
Waterbury AL, Kwok HS, Lee C, Narducci DN, Freedy AM, Su C, Raval S, Reiter AH, Hawkins W, Lee K, Li J, Hoenig SM, Vinyard ME, Cole PA, Hansen AS, Carr SA, Papanastasiou M, Liau BB. Waterbury AL, et al. Among authors: papanastasiou m. Mol Cell. 2024 Jun 20;84(12):2238-2254.e11. doi: 10.1016/j.molcel.2024.05.017. Epub 2024 Jun 12. Mol Cell. 2024. PMID: 38870936
Heterogeneity and transcriptional drivers of triple-negative breast cancer.
Jovanović B, Temko D, Stevens LE, Seehawer M, Fassl A, Murphy K, Anand J, Garza K, Gulvady A, Qiu X, Harper NW, Daniels VW, Xiao-Yun H, Ge JY, Alečković M, Pyrdol J, Hinohara K, Egri SB, Papanastasiou M, Vadhi R, Font-Tello A, Witwicki R, Peluffo G, Trinh A, Shu S, Diciaccio B, Ekram MB, Subedee A, Herbert ZT, Wucherpfennig KW, Letai AG, Jaffe JD, Sicinski P, Brown M, Dillon D, Long HW, Michor F, Polyak K. Jovanović B, et al. Among authors: papanastasiou m. Cell Rep. 2023 Dec 26;42(12):113564. doi: 10.1016/j.celrep.2023.113564. Epub 2023 Dec 14. Cell Rep. 2023. PMID: 38100350 Free PMC article.
41 results