Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

12 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Structure-Based Development of Novel Spiro-Piperidine ASH1L Inhibitors.
Huang G, Stevens R, Hucek DG, Purohit T, Li S, Miao H, Trost E, Hewett G, Clegg B, Park SR, Rajanayake K, Wen B, Sun D, Cierpicki T, Grembecka J. Huang G, et al. Among authors: rajanayake k. J Med Chem. 2025 Jan 9;68(1):174-195. doi: 10.1021/acs.jmedchem.4c01673. Epub 2024 Dec 16. J Med Chem. 2025. PMID: 39680643
Studies of Structure-Activity Relationship of 2-(Pyrrolidin-1ylmethyl)-1H-pyrrole-Based ST2 Inhibitors and Their Inhibition of Mast Cells Activation.
Yuan X, Rech JC, Ramaraju A, Patil AD, Rajanayake K, Yuan H, Kazemi Sabzvar M, Mandal M, Cho EB, Wen B, Jiang J, Leo MD, Singh UP, Sun D, Yang CY. Yuan X, et al. Among authors: rajanayake k. ACS Med Chem Lett. 2024 Oct 18;15(11):2053-2059. doi: 10.1021/acsmedchemlett.4c00459. eCollection 2024 Nov 14. ACS Med Chem Lett. 2024. PMID: 39563831
Morphomics-informed population pharmacokinetic and physiologically-based pharmacokinetic modeling to optimize cefazolin surgical prophylaxis.
Liu S, Matvekas A, Naimi T, Ghanem A, Li R, Rajanayake K, Derstine B, Ross B, Sullivan J, Yun HG, Regenbogen S, Byrn J, Su G, Wang S, Pai MP. Liu S, et al. Among authors: rajanayake k. Pharmacotherapy. 2024 Jan;44(1):77-86. doi: 10.1002/phar.2878. Epub 2023 Sep 29. Pharmacotherapy. 2024. PMID: 37728152 Free PMC article.
Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors.
Yuan X, Jiang H, Fu D, Rech JC, Robida A, Rajanayake K, Yuan H, He M, Wen B, Sun D, Liu C, Chinnaswamy K, Stuckey JA, Paczesny S, Yang CY. Yuan X, et al. Among authors: rajanayake k. ACS Pharmacol Transl Sci. 2023 Aug 16;6(9):1275-1287. doi: 10.1021/acsptsci.3c00122. eCollection 2023 Sep 8. ACS Pharmacol Transl Sci. 2023. PMID: 37705593 Free PMC article.
Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.
Yuan X, Jiang H, Fu D, Robida A, Rajanayake K, Yuan H, Wen B, Sun D, Watch BT, Chinnaswamy K, Stuckey JA, Paczesny S, Rech JC, Yang CY. Yuan X, et al. Among authors: rajanayake k. Bioorg Med Chem. 2022 Oct 1;71:116942. doi: 10.1016/j.bmc.2022.116942. Epub 2022 Jul 22. Bioorg Med Chem. 2022. PMID: 35930851 Free PMC article.
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.
Rom O, Liu Y, Finney AC, Ghrayeb A, Zhao Y, Shukha Y, Wang L, Rajanayake KK, Das S, Rashdan NA, Weissman N, Delgadillo L, Wen B, Garcia-Barrio MT, Aviram M, Kevil CG, Yurdagul A Jr, Pattillo CB, Zhang J, Sun D, Hayek T, Gottlieb E, Mor I, Chen YE. Rom O, et al. Among authors: rajanayake kk. Redox Biol. 2022 Jun;52:102313. doi: 10.1016/j.redox.2022.102313. Epub 2022 Apr 13. Redox Biol. 2022. PMID: 35447412 Free PMC article.
12 results