Clarke CJ - Search Results

1

Remote organ cancer induces kidney injury, inflammation, and fibrosis and adversely alters renal function.

Hammouri D, Orwick A, Doll MA, Sanchez Vega D, Shah PP, Clarke CJ, Clem B, Beverly LJ, Siskind LJ. Hammouri D, et al. Among authors: clarke cj. Am J Physiol Renal Physiol. 2024 Dec 16. Online ahead of print. Am J Physiol Renal Physiol. 2024. PMID: 39681358

2

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.

Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ. Dupre TV, et al. Among authors: clarke cj. J Lipid Res. 2017 Jul;58(7):1439-1452. doi: 10.1194/jlr.M076745. Epub 2017 May 10. J Lipid Res. 2017. PMID: 28490444 Free PMC article.

3

Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis.

Chipuk JE, McStay GP, Bharti A, Kuwana T, Clarke CJ, Siskind LJ, Obeid LM, Green DR. Chipuk JE, et al. Among authors: clarke cj. Cell. 2012 Mar 2;148(5):988-1000. doi: 10.1016/j.cell.2012.01.038. Cell. 2012. PMID: 22385963 Free PMC article.

4

The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis.

Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, Hernandez-Corbacho MJ, Edinger AL, Obeid LM. Siskind LJ, et al. Among authors: clarke cj. J Biol Chem. 2010 Apr 16;285(16):11818-26. doi: 10.1074/jbc.M109.078121. Epub 2010 Feb 18. J Biol Chem. 2010. PMID: 20172858 Free PMC article.

5

Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction.

Hernández-Corbacho MJ, Jenkins RW, Clarke CJ, Hannun YA, Obeid LM, Snider AJ, Siskind LJ. Hernández-Corbacho MJ, et al. Among authors: clarke cj. PLoS One. 2011;6(6):e20411. doi: 10.1371/journal.pone.0020411. Epub 2011 Jun 8. PLoS One. 2011. PMID: 21687659 Free PMC article.

6

Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases.

Mohammed S, Shamseddine AA, Newcomb B, Chavez RS, Panzner TD, Lee AH, Canals D, Okeoma CM, Clarke CJ, Hannun YA. Mohammed S, et al. Among authors: clarke cj. Breast Cancer Res. 2021 Jul 27;23(1):76. doi: 10.1186/s13058-021-01452-5. Breast Cancer Res. 2021. PMID: 34315513 Free PMC article.

7

Dihydroceramide desaturase 1 (DES1) promotes anchorage-independent survival downstream of HER2-driven glucose uptake and metabolism.

Linzer RW, Guida DL, Aminov J, Snider JM, Khalife G, Buyukbayraktar AB, Alhaddad C, Resnick AE, Wang P, Pan CH, Allopenna JJ, Clarke CJ. Linzer RW, et al. Among authors: clarke cj. FASEB J. 2022 Oct;36(10):e22558. doi: 10.1096/fj.202200748R. FASEB J. 2022. PMID: 36165222 Free PMC article.

8

Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor.

Liu M, Idkowiak-Baldys J, Roddy PL, Baldys A, Raymond J, Clarke CJ, Hannun YA. Liu M, et al. Among authors: clarke cj. PLoS One. 2013 Nov 11;8(11):e80721. doi: 10.1371/journal.pone.0080721. eCollection 2013. PLoS One. 2013. PMID: 24244711 Free PMC article.

9

PKCα is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation.

Salama MF, Liu M, Clarke CJ, Espaillat MP, Haley JD, Jin T, Wang D, Obeid LM, Hannun YA. Salama MF, et al. Among authors: clarke cj. Oncogene. 2019 Nov;38(48):7311-7328. doi: 10.1038/s41388-019-0950-z. Epub 2019 Aug 16. Oncogene. 2019. PMID: 31420605 Free PMC article.

10

Neutral Sphingomyelinases in Cancer: Friend or Foe?

Clarke CJ. Clarke CJ. Adv Cancer Res. 2018;140:97-119. doi: 10.1016/bs.acr.2018.04.010. Epub 2018 May 28. Adv Cancer Res. 2018. PMID: 30060818 Review.

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