Suzuki Y - Search Results

1

Deficiencies of Inducible Costimulator (ICOS) During Chronic Infection with Toxoplasma gondii Upregulate the CD28-Dependent Cytotoxicity of CD8⁺ T Cells and Their Effector Function Against Tissue Cysts of the Parasite.

Mani R, Balu KE, Suzuki Y. Mani R, et al. Among authors: suzuki y. Cells. 2024 Dec 3;13(23):1998. doi: 10.3390/cells13231998. Cells. 2024. PMID: 39682747 Free PMC article.

2

Human MHC class I molecule, HLA-A2.1, mediates activation of CD8⁺ T cell IFN-γ production and the T cell-dependent protection against reactivation of cerebral Toxoplasma infection.

Mani R, Abdelaziz MH, Michelon A, Suzuki Y. Mani R, et al. Among authors: suzuki y. Front Immunol. 2022 Oct 13;13:1005059. doi: 10.3389/fimmu.2022.1005059. eCollection 2022. Front Immunol. 2022. PMID: 36311799 Free PMC article.

3

Immunization with the amino-terminus region of dense granule protein 6 (GRA6) of Toxoplasma gondii activates CD8⁺ cytotoxic T cells capable of removing tissue cysts of the parasite through antigen presentation by human HLA-A2.1.

Mani R, Mercier C, Delauw MF, Suzuki Y. Mani R, et al. Among authors: suzuki y. Microbes Infect. 2023 Nov-Dec;25(8):105182. doi: 10.1016/j.micinf.2023.105182. Epub 2023 Jul 8. Microbes Infect. 2023. PMID: 37423326 Free article.

4

Dense granule protein 3 of Toxoplasma gondii plays a crucial role in the capability of the tissue cysts of the parasite to persist in the presence of anti-cyst CD8⁺ T cells during the chronic stage of infection.

Mani R, Abdelaziz MH, Ochiai E, Sa Q, Fox BA, Bzik DJ, Suzuki Y. Mani R, et al. Among authors: suzuki y. Front Immunol. 2023 Oct 5;14:1272221. doi: 10.3389/fimmu.2023.1272221. eCollection 2023. Front Immunol. 2023. PMID: 37868957 Free PMC article.

5

The Absence of CXCL10 Activity Does Not Affect the Capability of CD8⁺ T Cells to Migrate and Eliminate the Tissue Cysts of Toxoplasma gondii from the Brains of Chronically Infected Mice.

Mani R, Suzuki Y. Mani R, et al. Among authors: suzuki y. Microorganisms. 2024 Oct 29;12(11):2172. doi: 10.3390/microorganisms12112172. Microorganisms. 2024. PMID: 39597561 Free PMC article.

6

Deficiency in indoleamine-2, 3-dioxygenase induces upregulation of guanylate binding protein 1 and inducible nitric oxide synthase expression in the brain during cerebral infection with Toxoplasma gondii in genetically resistant BALB/c mice but not in genetically susceptible C57BL/6 mice.

Anand N, Lutshumba J, Whitlow M, Abdelaziz MH, Mani R, Suzuki Y. Anand N, et al. Among authors: suzuki y. Microbes Infect. 2022 Apr-May;24(3):104908. doi: 10.1016/j.micinf.2021.104908. Epub 2021 Nov 13. Microbes Infect. 2022. PMID: 34781010 Free PMC article.

7

Penetration of CD8⁺ Cytotoxic T Cells into Large Target, Tissue Cysts of Toxoplasma gondii, Leads to Its Elimination.

Tiwari A, Hannah R, Lutshumba J, Ochiai E, Weiss LM, Suzuki Y. Tiwari A, et al. Among authors: suzuki y. Am J Pathol. 2019 Aug;189(8):1594-1607. doi: 10.1016/j.ajpath.2019.04.018. Epub 2019 Jul 10. Am J Pathol. 2019. PMID: 31301754 Free PMC article.

8

Removal of Toxoplasma gondii cysts from the brain by perforin-mediated activity of CD8+ T cells.

Suzuki Y, Wang X, Jortner BS, Payne L, Ni Y, Michie SA, Xu B, Kudo T, Perkins S. Suzuki Y, et al. Am J Pathol. 2010 Apr;176(4):1607-13. doi: 10.2353/ajpath.2010.090825. Epub 2010 Feb 18. Am J Pathol. 2010. PMID: 20167872 Free PMC article.

9

CD8(+) T cells remove cysts of Toxoplasma gondii from the brain mostly by recognizing epitopes commonly expressed by or cross-reactive between type II and type III strains of the parasite.

Ochiai E, Sa Q, Perkins S, Grigg ME, Suzuki Y. Ochiai E, et al. Among authors: suzuki y. Microbes Infect. 2016 Jul-Aug;18(7-8):517-22. doi: 10.1016/j.micinf.2016.03.013. Epub 2016 Apr 12. Microbes Infect. 2016. PMID: 27083473 Free PMC article.

10

A pathway to cure chronic infection with Toxoplasma gondii through immunological intervention.

Suzuki Y. Suzuki Y. Parasitol Int. 2021 Apr;81:102259. doi: 10.1016/j.parint.2020.102259. Epub 2020 Dec 1. Parasitol Int. 2021. PMID: 33271362 Free PMC article. Review.

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