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Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.
Linciano P, Sorbi C, Rossino G, Rossi D, Marsala A, Denora N, Bedeschi M, Marino N, Miserocchi G, Dondio G, Peviani M, Tesei A, Collina S, Franchini S. Linciano P, et al. Among authors: sorbi c. Eur J Med Chem. 2023 Mar 5;249:115163. doi: 10.1016/j.ejmech.2023.115163. Epub 2023 Jan 26. Eur J Med Chem. 2023. PMID: 36716640 Free article.
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting.
Sorbi C, Belluti S, Atene CG, Marocchi F, Linciano P, Roy N, Paradiso E, Casarini L, Ronsisvalle S, Zanocco-Marani T, Brasili L, Lanfrancone L, Imbriano C, Di Rocco G, Franchini S. Sorbi C, et al. Int J Mol Sci. 2023 Jun 2;24(11):9684. doi: 10.3390/ijms24119684. Int J Mol Sci. 2023. PMID: 37298633 Free PMC article.
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity.
Franchini S, Sorbi C, Linciano P, Carnevale G, Tait A, Ronsisvalle S, Buccioni M, Del Bello F, Cilia A, Pirona L, Denora N, Iacobazzi RM, Brasili L. Franchini S, et al. Among authors: sorbi c. Eur J Med Chem. 2019 Aug 15;176:310-325. doi: 10.1016/j.ejmech.2019.05.024. Epub 2019 May 11. Eur J Med Chem. 2019. PMID: 31112892
Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.
Franchini S, Sorbi C, Battisti UM, Tait A, Bencheva LI, Cichero E, Fossa P, Cilia A, Prezzavento O, Ronsisvalle S, Aricò G, Benassi L, Vaschieri C, Azzoni P, Magnoni C, Brasili L. Franchini S, et al. Among authors: sorbi c. ChemMedChem. 2017 Nov 22;12(22):1893-1905. doi: 10.1002/cmdc.201700427. Epub 2017 Oct 30. ChemMedChem. 2017. PMID: 28940806 Free article.
30 results