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Dextromethorphan inhibits collagen and collagen-like cargo secretion to ameliorate lung fibrosis.
Khan MM, Galea G, Jung J, Zukowska J, Lauer D, Tuechler N, Halavatyi A, Tischer C, Haberkant P, Stein F, Jung F, Landry JJM, Khan AM, Oorschot V, Becher I, Neumann B, Muley T, Winter H, Duerr J, Mall MA, Grassi A, de la Cueva E, Benes V, Gote-Schniering J, Savitski M, Pepperkok R. Khan MM, et al. Among authors: duerr j. Sci Transl Med. 2024 Dec 18;16(778):eadj3087. doi: 10.1126/scitranslmed.adj3087. Epub 2024 Dec 18. Sci Transl Med. 2024. PMID: 39693409
Lung arginase expression and activity is increased in cystic fibrosis mouse models.
Jaecklin T, Duerr J, Huang H, Rafii M, Bear CE, Ratjen F, Pencharz P, Kavanagh BP, Mall MA, Grasemann H. Jaecklin T, et al. Among authors: duerr j. J Appl Physiol (1985). 2014 Aug 1;117(3):284-8. doi: 10.1152/japplphysiol.00167.2014. Epub 2014 Jun 12. J Appl Physiol (1985). 2014. PMID: 24925982 Free article.
Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Duerr J, Leitz DHW, Szczygiel M, Dvornikov D, Fraumann SG, Kreutz C, Zadora PK, Seyhan Agircan A, Konietzke P, Engelmann TA, Hegermann J, Mulugeta S, Kawabe H, Knudsen L, Ochs M, Rotin D, Muley T, Kreuter M, Herth FJF, Wielpütz MO, Beers MF, Klingmüller U, Mall MA. Duerr J, et al. Nat Commun. 2020 Apr 24;11(1):2012. doi: 10.1038/s41467-020-15743-6. Nat Commun. 2020. PMID: 32332792 Free PMC article.
Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopy.
D'Amico L, Svetlove A, Longo E, Meyer R, Senigagliesi B, Saccomano G, Nolte P, Wagner WL, Wielpütz MO, Leitz DHW, Duerr J, Mall MA, Casalis L, Köster S, Alves F, Tromba G, Dullin C. D'Amico L, et al. Among authors: duerr j. Comput Biol Med. 2024 Feb;169:107947. doi: 10.1016/j.compbiomed.2024.107947. Epub 2024 Jan 8. Comput Biol Med. 2024. PMID: 38211385 Free article.
Longitudinal microcomputed tomography detects onset and progression of pulmonary fibrosis in conditional Nedd4-2 deficient mice.
Leitz DHW, Konietzke P, Wagner WL, Mertiny M, Benke C, Schneider T, Morty RE, Dullin C, Stiller W, Kauczor HU, Mall MA, Duerr J, Wielpütz MO. Leitz DHW, et al. Among authors: duerr j. Am J Physiol Lung Cell Mol Physiol. 2024 Dec 1;327(6):L917-L929. doi: 10.1152/ajplung.00280.2023. Epub 2024 Oct 22. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 39437758 Free article.
The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
Zhou Z, Duerr J, Johannesson B, Schubert SC, Treis D, Harm M, Graeber SY, Dalpke A, Schultz C, Mall MA. Zhou Z, et al. Among authors: duerr j. J Cyst Fibros. 2011 Jun;10 Suppl 2:S172-82. doi: 10.1016/S1569-1993(11)60021-0. J Cyst Fibros. 2011. PMID: 21658636 Free article. Review.
84 results