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Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy.
Mbacham WF, Evehe MS, Netongo PM, Ateh IA, Mimche PN, Ajua A, Nji AM, Irenee D, Echouffo-Tcheugui JB, Tawe B, Hallett R, Roper C, Targett G, Greenwood B. Mbacham WF, et al. Among authors: roper c. Malar J. 2010 Jan 27;9:34. doi: 10.1186/1475-2875-9-34. Malar J. 2010. PMID: 20105282 Free PMC article. Clinical Trial.
Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon.
Martinez-Vega R, Mbacham WF, Ali I, Nji A, Mousa A, Beshir KB, Chopo-Pizarro A, Kaur H, Okell L, Hansson H, Hocke EF, Alifrangis M, Gosling R, Roper C, Sutherland C, Chico RM. Martinez-Vega R, et al. Among authors: roper c. BMC Infect Dis. 2024 Sep 26;24(1):1028. doi: 10.1186/s12879-024-09868-y. BMC Infect Dis. 2024. PMID: 39327613 Free PMC article. Clinical Trial.
Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology.
Mousa A, Cuomo-Dannenburg G, Thompson HA, Chico RM, Beshir KB, Sutherland CJ, Schellenberg D, Gosling R, Alifrangis M, Hocke EF, Hansson H, Chopo-Pizarro A, Mbacham WF, Ali IM, Chaponda M, Roper C, Okell LC. Mousa A, et al. Among authors: roper c. PLoS Med. 2024 May 9;21(5):e1004376. doi: 10.1371/journal.pmed.1004376. eCollection 2024 May. PLoS Med. 2024. PMID: 38723040 Free PMC article.
Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria.
Pearce RJ, Pota H, Evehe MS, Bâ el-H, Mombo-Ngoma G, Malisa AL, Ord R, Inojosa W, Matondo A, Diallo DA, Mbacham W, van den Broek IV, Swarthout TD, Getachew A, Dejene S, Grobusch MP, Njie F, Dunyo S, Kweku M, Owusu-Agyei S, Chandramohan D, Bonnet M, Guthmann JP, Clarke S, Barnes KI, Streat E, Katokele ST, Uusiku P, Agboghoroma CO, Elegba OY, Cissé B, A-Elbasit IE, Giha HA, Kachur SP, Lynch C, Rwakimari JB, Chanda P, Hawela M, Sharp B, Naidoo I, Roper C. Pearce RJ, et al. Among authors: roper c. PLoS Med. 2009 Apr 14;6(4):e1000055. doi: 10.1371/journal.pmed.1000055. Epub 2009 Apr 14. PLoS Med. 2009. PMID: 19365539 Free PMC article.
The polymorphic linker domain of pfmdr1 is associated with resistance-conferring mutations in Plasmodium falciparum populations from East and West Africa.
Okombo J, Zongo I, Gadalla N, Bousema T, Beshir KB, Roper C, Hallett R, Ochola-Oyier LI, Sutherland CJ. Okombo J, et al. Among authors: roper c. Antimicrob Agents Chemother. 2013 Sep;57(9):4595-8. doi: 10.1128/AAC.00455-13. Epub 2013 Jul 8. Antimicrob Agents Chemother. 2013. PMID: 23836177 Free PMC article.
Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V.
Oguike MC, Falade CO, Shu E, Enato IG, Watila I, Baba ES, Bruce J, Webster J, Hamade P, Meek S, Chandramohan D, Sutherland CJ, Warhurst D, Roper C. Oguike MC, et al. Among authors: roper c. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):220-229. doi: 10.1016/j.ijpddr.2016.08.004. Epub 2016 Sep 29. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27821281 Free PMC article.
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data.
WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group; Dahal P, d'Alessandro U, Dorsey G, Guerin PJ, Nsanzabana C, Price RN, Sibley CH, Stepniewska K, Talisuna AO. WWARN Artemisinin based Combination Therapy (ACT) Africa Baseline Study Group, et al. BMC Med. 2015 Sep 7;13:212. doi: 10.1186/s12916-015-0445-x. BMC Med. 2015. PMID: 26343145 Free PMC article. Review.
312 results