Totah RA - Search Results

1

Editorial: Cytochromes P450, their modulators and metabolites in cardiovascular function and disease.

Adebesin AM, Roman RJ, Campbell WB, Seubert JM, Totah RA. Adebesin AM, et al. Among authors: totah ra. Front Pharmacol. 2024 Dec 3;15:1531166. doi: 10.3389/fphar.2024.1531166. eCollection 2024. Front Pharmacol. 2024. PMID: 39697552 Free PMC article. No abstract available.

2

The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.

Robey RW, Fitzsimmons CM, Guiblet WM, Frye WJE, González Dalmasy JM, Wang L, Russell DA, Huff LM, Perciaccante AJ, Ali-Rahmani F, Lipsey CC, Wade HM, Mitchell AV, Maligireddy SS, Terrero D, Butcher D, Edmondson EF, Jenkins LM, Nikitina T, Zhurkin VB, Tiwari AK, Piscopio AD, Totah RA, Bates SE, Arda HE, Gottesman MM, Batista PJ. Robey RW, et al. Among authors: totah ra. Mol Cancer Ther. 2024 Apr 2;23(4):464-477. doi: 10.1158/1535-7163.MCT-23-0144. Mol Cancer Ther. 2024. PMID: 38151817 Free PMC article.

3

Identification of novel substrates for human cytochrome P450 2J2.

Lee CA, Neul D, Clouser-Roche A, Dalvie D, Wester MR, Jiang Y, Jones JP 3rd, Freiwald S, Zientek M, Totah RA. Lee CA, et al. Among authors: totah ra. Drug Metab Dispos. 2010 Feb;38(2):347-56. doi: 10.1124/dmd.109.030270. Epub 2009 Nov 18. Drug Metab Dispos. 2010. PMID: 19923256

4

Cytochrome P450s: new insights and relevance to medicinal chemistry and drug discovery.

Totah RA. Totah RA. Curr Top Med Chem. 2013;13(12):1363. doi: 10.2174/1568026611313120001. Curr Top Med Chem. 2013. PMID: 23688129 No abstract available.

5

Detection of aminium ion intermediates: N-cyclopropyl versus N-carboxymethyl groups as reporters.

Totah RA, Hanzlik RP. Totah RA, et al. J Am Chem Soc. 2001 Oct 17;123(41):10107-8. doi: 10.1021/ja011648u. J Am Chem Soc. 2001. PMID: 11592894 No abstract available.

6

Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors.

Evangelista EA, Cho CW, Aliwarga T, Totah RA. Evangelista EA, et al. Among authors: totah ra. Front Pharmacol. 2020 Jun 9;11:828. doi: 10.3389/fphar.2020.00828. eCollection 2020. Front Pharmacol. 2020. PMID: 32581794 Free PMC article. Review.

7

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5.

Kaspera R, Naraharisetti SB, Evangelista EA, Marciante KD, Psaty BM, Totah RA. Kaspera R, et al. Among authors: totah ra. Biochem Pharmacol. 2011 Sep 15;82(6):681-91. doi: 10.1016/j.bcp.2011.06.027. Epub 2011 Jun 24. Biochem Pharmacol. 2011. PMID: 21726541 Free PMC article.

8

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.

Totah RA, Rettie AE. Totah RA, et al. Clin Pharmacol Ther. 2005 May;77(5):341-52. doi: 10.1016/j.clpt.2004.12.267. Clin Pharmacol Ther. 2005. PMID: 15900280 Review.

9

Cardioprotective mechanisms of cytochrome P450 derived oxylipins from ω-3 and ω-6 PUFAs.

Cho C, Aliwarga T, Wiley AM, Totah RA. Cho C, et al. Among authors: totah ra. Adv Pharmacol. 2023;97:201-227. doi: 10.1016/bs.apha.2023.02.001. Epub 2023 Mar 27. Adv Pharmacol. 2023. PMID: 37236759

10

Enantiomeric metabolic interactions and stereoselective human methadone metabolism.

Totah RA, Allen KE, Sheffels P, Whittington D, Kharasch ED. Totah RA, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):389-99. doi: 10.1124/jpet.106.117580. Epub 2007 Jan 26. J Pharmacol Exp Ther. 2007. PMID: 17259447 Free article.

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