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Repurposing Drugs and Synergistic Combinations as Potential Therapies for Inhibiting SARS-CoV-2 and Coronavirus Replication.
Boulon R, Mazeaud C, Farahani MD, Broquière M, Iddir M, Charpentier T, Anton A, Ayotte Y, Woo S, Lamarre A, Chatel-Chaix L, LaPlante SR. Boulon R, et al. Among authors: woo s. ACS Pharmacol Transl Sci. 2024 Nov 5;7(12):4043-4055. doi: 10.1021/acsptsci.4c00512. eCollection 2024 Dec 13. ACS Pharmacol Transl Sci. 2024. PMID: 39698276
N-Phenylpyridine-3-Carboxamide and 6-Acetyl-1H-Indazole Inhibit the RNA Replication Step of the Dengue Virus Life Cycle.
Sow AA, Pahmeier F, Ayotte Y, Anton A, Mazeaud C, Charpentier T, Angelo L, Woo S, Cerikan B, Falzarano D, Abrahamyan L, Lamarre A, Labonté P, Cortese M, Bartenschlager R, LaPlante SR, Chatel-Chaix L. Sow AA, et al. Among authors: woo s. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0133122. doi: 10.1128/aac.01331-22. Epub 2023 Jan 26. Antimicrob Agents Chemother. 2023. PMID: 36700643 Free PMC article.
Robust Strategy for Hit-to-Lead Discovery: NMR for SAR.
Larda ST, Ayotte Y, Denk MM, Coote P, Heffron G, Bendahan D, Shahout F, Girard N, Iddir M, Bouchard P, Bilodeau F, Woo S, Farmer LJ, LaPlante SR. Larda ST, et al. Among authors: woo s. J Med Chem. 2023 Oct 12;66(19):13416-13427. doi: 10.1021/acs.jmedchem.3c00656. Epub 2023 Sep 21. J Med Chem. 2023. PMID: 37732695 Free PMC article.
Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid.
Mélin L, Abdullayev S, Fnaiche A, Vu V, González Suárez N, Zeng H, Szewczyk MM, Li F, Senisterra G, Allali-Hassani A, Chau I, Dong A, Woo S, Annabi B, Halabelian L, LaPlante SR, Vedadi M, Barsyte-Lovejoy D, Santhakumar V, Gagnon A. Mélin L, et al. Among authors: woo s. ChemMedChem. 2021 Oct 6;16(19):2982-3002. doi: 10.1002/cmdc.202100432. Epub 2021 Jul 28. ChemMedChem. 2021. PMID: 34164919
4,713 results