Kleigrewe K - Search Results

1

Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism.

Bordes J, Bajaj T, Miranda L, van Doeselaar L, Brix LM, Narayan S, Yang H, Mitra S, Kovarova V, Springer M, Kleigrewe K, Müller-Myhsok B, Gassen NC, Schmidt MV. Bordes J, et al. Among authors: kleigrewe k. Commun Biol. 2024 Dec 20;7(1):1684. doi: 10.1038/s42003-024-07396-8. Commun Biol. 2024. PMID: 39702524 Free PMC article.

2

Pseudomonas putida as saviour for troubled Synechococcus elongatus in a synthetic co-culture - interaction studies based on a multi-OMICs approach.

Kratzl F, Urban M, Pandhal J, Shi M, Meng C, Kleigrewe K, Kremling A, Pflüger-Grau K. Kratzl F, et al. Among authors: kleigrewe k. Commun Biol. 2024 Apr 12;7(1):452. doi: 10.1038/s42003-024-06098-5. Commun Biol. 2024. PMID: 38609451 Free PMC article.

3

Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community.

Weiss AS, Niedermeier LS, von Strempel A, Burrichter AG, Ring D, Meng C, Kleigrewe K, Lincetto C, Hübner J, Stecher B. Weiss AS, et al. Among authors: kleigrewe k. Nat Commun. 2023 Aug 8;14(1):4780. doi: 10.1038/s41467-023-40372-0. Nat Commun. 2023. PMID: 37553336 Free PMC article.

4

DIAMetAlyzer allows automated false-discovery rate-controlled analysis for data-independent acquisition in metabolomics.

Alka O, Shanthamoorthy P, Witting M, Kleigrewe K, Kohlbacher O, Röst HL. Alka O, et al. Among authors: kleigrewe k. Nat Commun. 2022 Mar 15;13(1):1347. doi: 10.1038/s41467-022-29006-z. Nat Commun. 2022. PMID: 35292629 Free PMC article.

5

The intestinal clock drives the microbiome to maintain gastrointestinal homeostasis.

Heddes M, Altaha B, Niu Y, Reitmeier S, Kleigrewe K, Haller D, Kiessling S. Heddes M, et al. Among authors: kleigrewe k. Nat Commun. 2022 Oct 14;13(1):6068. doi: 10.1038/s41467-022-33609-x. Nat Commun. 2022. PMID: 36241650 Free PMC article.

6

The Genetic Background Is Shaping Cecal Enlargement in the Absence of Intestinal Microbiota.

Bolsega S, Smoczek A, Meng C, Kleigrewe K, Scheele T, Meller S, Glage S, Volk HA, Bleich A, Basic M. Bolsega S, et al. Among authors: kleigrewe k. Nutrients. 2023 Jan 26;15(3):636. doi: 10.3390/nu15030636. Nutrients. 2023. PMID: 36771343 Free PMC article.

7

Development of a Global Metabo-Lipid-Prote-omics Workflow to Compare Healthy Proximal and Distal Colonic Epithelium in Mice.

Hemmati M, Wudy SI, Hackbarth F, Mittermeier-Kleßinger VK, Coleman OI, Haller D, Ludwig C, Dawid C, Kleigrewe K. Hemmati M, et al. Among authors: kleigrewe k. J Proteome Res. 2024 Aug 2;23(8):3124-3140. doi: 10.1021/acs.jproteome.3c00771. Epub 2024 Jul 25. J Proteome Res. 2024. PMID: 39052308 Free PMC article.

8

Proteome activity landscapes of tumor cell lines determine drug responses.

Frejno M, Meng C, Ruprecht B, Oellerich T, Scheich S, Kleigrewe K, Drecoll E, Samaras P, Hogrebe A, Helm D, Mergner J, Zecha J, Heinzlmeir S, Wilhelm M, Dorn J, Kvasnicka HM, Serve H, Weichert W, Kuster B. Frejno M, et al. Among authors: kleigrewe k. Nat Commun. 2020 Jul 20;11(1):3639. doi: 10.1038/s41467-020-17336-9. Nat Commun. 2020. PMID: 32686665 Free PMC article.

9

Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target.

Lechner S, Malgapo MIP, Grätz C, Steimbach RR, Baron A, Rüther P, Nadal S, Stumpf C, Loos C, Ku X, Prokofeva P, Lautenbacher L, Heimburg T, Würf V, Meng C, Wilhelm M, Sippl W, Kleigrewe K, Pauling JK, Kramer K, Miller AK, Pfaffl MW, Linder ME, Kuster B, Médard G. Lechner S, et al. Among authors: kleigrewe k. Nat Chem Biol. 2022 Aug;18(8):812-820. doi: 10.1038/s41589-022-01015-5. Epub 2022 Apr 28. Nat Chem Biol. 2022. PMID: 35484434 Free PMC article.

10

Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activity.

Fromme T, Kleigrewe K, Dunkel A, Retzler A, Li Y, Maurer S, Fischer N, Diezko R, Kanzleiter T, Hirschberg V, Hofmann T, Klingenspor M. Fromme T, et al. Among authors: kleigrewe k. Mol Metab. 2018 Feb;8:77-85. doi: 10.1016/j.molmet.2017.12.010. Epub 2017 Dec 26. Mol Metab. 2018. PMID: 29310935 Free PMC article.

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