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A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes.
Scherschel M, Niemeier JO, Jacobs LJHC, Hoffmann MDA, Diederich A, Bell C, Höhne P, Raetz S, Kroll JB, Steinbeck J, Lichtenauer S, Multhoff J, Zimmermann J, Sadhanasatish T, Rothemann RA, Grashoff C, Messens J, Ampofo E, Laschke MW, Riemer J, Roma LP, Schwarzländer M, Morgan B. Scherschel M, et al. Among authors: zimmermann j. Nat Commun. 2024 Dec 19;15(1):10704. doi: 10.1038/s41467-024-55302-x. Nat Commun. 2024. PMID: 39702652 Free PMC article.
Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast.
Zimmermann J, Lang L, Calabrese G, Laporte H, Amponsah PS, Michalk C, Sukmann T, Oestreicher J, Tursch A, Peker E, Owusu TNE, Weith M, Roma LP, Deponte M, Riemer J, Morgan B. Zimmermann J, et al. Free Radic Biol Med. 2025 Jan;226:408-420. doi: 10.1016/j.freeradbiomed.2024.11.004. Epub 2024 Nov 6. Free Radic Biol Med. 2025. PMID: 39515595 Free article.
Peroxiredoxins couple metabolism and cell division in an ultradian cycle.
Amponsah PS, Yahya G, Zimmermann J, Mai M, Mergel S, Mühlhaus T, Storchova Z, Morgan B. Amponsah PS, et al. Among authors: zimmermann j. Nat Chem Biol. 2021 Apr;17(4):477-484. doi: 10.1038/s41589-020-00728-9. Epub 2021 Feb 11. Nat Chem Biol. 2021. PMID: 33574615
The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import.
Rödl S, den Brave F, Räschle M, Kizmaz B, Lenhard S, Groh C, Becker H, Zimmermann J, Morgan B, Richling E, Becker T, Herrmann JM. Rödl S, et al. Among authors: zimmermann j. Life Sci Alliance. 2022 Oct 17;6(1):e202201526. doi: 10.26508/lsa.202201526. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36253107 Free PMC article.
1,193 results