Robertson AA - Search Results

1

Therapeutic Potential of MCC950 in Restoring Autophagy and Cognitive Function in STZ-Induced Rat Model of Alzheimer's Disease.

Naeem A, Waseem A, Khan MA, Robertson AA, Raza SS. Naeem A, et al. Among authors: robertson aa. Mol Neurobiol. 2024 Dec 20. doi: 10.1007/s12035-024-04662-y. Online ahead of print. Mol Neurobiol. 2024. PMID: 39702834

2

MCC950 Regulates Stem Cells Destiny Through Modulating SIRT3-NLRP3 Inflammasome Dynamics During Oxygen Glucose Deprivation.

Prakash R, Kumari N, Siddiqui AJ, Khan AQ, Khan MA, Khan R, Haque R, Robertson AA, Boltze J, Raza SS. Prakash R, et al. Among authors: robertson aa. Stem Cell Rev Rep. 2023 Jul;19(5):1415-1426. doi: 10.1007/s12015-023-10520-6. Epub 2023 Feb 22. Stem Cell Rev Rep. 2023. PMID: 36811746

3

NLRP3 Inflammasome-Targeting Nanomicelles for Preventing Ischemia-Reperfusion-Induced Inflammatory Injury.

Prakash R, Vyawahare A, Sakla R, Kumari N, Kumar A, Ansari MM, Kanika, Jori C, Waseem A, Siddiqui AJ, Khan MA, Robertson AAB, Khan R, Raza SS. Prakash R, et al. ACS Nano. 2023 May 9;17(9):8680-8693. doi: 10.1021/acsnano.3c01760. Epub 2023 Apr 27. ACS Nano. 2023. PMID: 37102996

4

Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism.

Fauzia E, Barbhuyan TK, Shrivastava AK, Kumar M, Garg P, Khan MA, Robertson AAB, Raza SS. Fauzia E, et al. Front Pharmacol. 2018 Sep 21;9:1034. doi: 10.3389/fphar.2018.01034. eCollection 2018. Front Pharmacol. 2018. PMID: 30298003 Free PMC article.

5

The Small Molecule NLRP3 Inflammasome Inhibitor MCC950 Does Not Alter Wound Healing in Obese Mice.

Lee JS, Robertson AAB, Cooper MA, Khosrotehrani K. Lee JS, et al. Int J Mol Sci. 2018 Oct 23;19(11):3289. doi: 10.3390/ijms19113289. Int J Mol Sci. 2018. PMID: 30360489 Free PMC article.

6

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

Salla M, Butler MS, Pelingon R, Kaeslin G, Croker DE, Reid JC, Baek JM, Bernhardt PV, Gillam EM, Cooper MA, Robertson AA. Salla M, et al. Among authors: robertson aa. ACS Med Chem Lett. 2016 Sep 27;7(12):1034-1038. doi: 10.1021/acsmedchemlett.6b00198. eCollection 2016 Dec 8. ACS Med Chem Lett. 2016. PMID: 27994733 Free PMC article.

7

The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction.

van Hout GP, Bosch L, Ellenbroek GH, de Haan JJ, van Solinge WW, Cooper MA, Arslan F, de Jager SC, Robertson AA, Pasterkamp G, Hoefer IE. van Hout GP, et al. Among authors: robertson aa. Eur Heart J. 2017 Mar 14;38(11):828-836. doi: 10.1093/eurheartj/ehw247. Eur Heart J. 2017. PMID: 27432019

8

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

Dempsey C, Rubio Araiz A, Bryson KJ, Finucane O, Larkin C, Mills EL, Robertson AAB, Cooper MA, O'Neill LAJ, Lynch MA. Dempsey C, et al. Brain Behav Immun. 2017 Mar;61:306-316. doi: 10.1016/j.bbi.2016.12.014. Epub 2016 Dec 18. Brain Behav Immun. 2017. PMID: 28003153

9

Evidence against a role for NLRP3-driven islet inflammation in db/db mice.

Kammoun HL, Allen TL, Henstridge DC, Barre S, Coll RC, Lancaster GI, Cron L, Reibe S, Chan JY, Bensellam M, Laybutt DR, Butler MS, Robertson AAB, O'Neill LA, Cooper MA, Febbraio MA. Kammoun HL, et al. Mol Metab. 2018 Apr;10:66-73. doi: 10.1016/j.molmet.2018.02.001. Epub 2018 Feb 7. Mol Metab. 2018. PMID: 29478918 Free PMC article.

10

Compromised NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages.

Thygesen SJ, Takizawa KE, Robertson AAB, Sester DP, Stacey KJ. Thygesen SJ, et al. Immunol Cell Biol. 2019 Jan;97(1):17-28. doi: 10.1111/imcb.12193. Epub 2018 Aug 19. Immunol Cell Biol. 2019. PMID: 30052286

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