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Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer's disease.
Argiris G, Akinci M, Peña-Gómez C, Palpatzis E, Garcia-Prat M, Shekari M, Blennow K, Zetterberg H, Kollmorgen G, Quijano-Rubio C, Ashton NJ, Karikari TK, Brinkmalm-Westman A, Lantero-Rodriguez J, Fauria K, Sánchez-Benavides G, Grau-Rivera O, Suárez-Calvet M, Arenaza-Urquijo EM, Study FTA. Argiris G, et al. Among authors: karikari tk. Alzheimers Res Ther. 2024 Dec 23;16(1):274. doi: 10.1186/s13195-024-01629-y. Alzheimers Res Ther. 2024. PMID: 39716329 Free PMC article.
Multimodal neuroimaging biomarkers and subtle cognitive decline in a population-based cohort without dementia.
Weinstein AM, Fang F, Chang CH, Cohen A, Lopresti BJ, Laymon CM, Nadkarni NK, Aizenstein HJ, Villemagne VL, Ilyas Kamboh M, Elizabeth Shaaban C, Gogniat MA, Wu M, Karikari TK, Ganguli M, Snitz BE. Weinstein AM, et al. Among authors: karikari tk. J Alzheimers Dis. 2024 Dec 19:13872877241303926. doi: 10.1177/13872877241303926. Online ahead of print. J Alzheimers Dis. 2024. PMID: 39702989
Influence of medical conditions on the diagnostic accuracy of plasma p-tau217 and p-tau217/Aβ42.
Olvera-Rojas M, Sewell KR, Karikari TK, Huang H, Oberlin LE, Zeng X, Morris JK, Collins AM, Drake JA, Sutton BP, Kramer AF, Hillman CH, Vidoni ED, Burns JM, Kamboh MI, McAuley E, Marsland AL, Chen Y, Lafferty TK, Sehrawat A, Jakicic JM, Wan L, Kang C, Erickson KI. Olvera-Rojas M, et al. Among authors: karikari tk. Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14430. Online ahead of print. Alzheimers Dement. 2024. PMID: 39641408
Plasma p-tau212 as a biomarker of sporadic and Down Syndrome Alzheimer's disease.
Kac PR, Alcolea D, Montoliu-Gaya L, Fernández S, Rodriguez JL, Maure L, González-Ortiz F, Benejam B, Turton M, Barroeta I, Harrison P, Videla L, Ashton NJ, Lleó A, Zetterberg H, Carmona-Iragui M, Karikari TK, Fortea J, Blennow K. Kac PR, et al. Among authors: karikari tk. medRxiv [Preprint]. 2024 Nov 2:2024.10.31.24316469. doi: 10.1101/2024.10.31.24316469. medRxiv. 2024. PMID: 39574868 Free PMC article. Preprint.
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability.
Therriault J, Janelidze S, Benedet AL, Ashton NJ, Arranz Martínez J, Gonzalez-Escalante A, Bellaver B, Alcolea D, Vrillon A, Karim H, Mielke MM, Hyung Hong C, Roh HW, Contador J, Puig Pijoan A, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Lowe VJ, Karikari TK, Jonaitis E, Brum W, Tissot C, Servaes S, Rahmouni N, Macedo AC, Stevenson J, Fernandez-Arias J, Wang YT, Woo MS, Friese MA, Jia WL, Dumurgier J, Hourregue C, Cognat E, Ferreira PL, Vitali P, Johnson S, Pascoal TA, Gauthier S, Lleó A, Paquet C, Petersen RC, Salmon D, Mattsson-Carlgren N, Palmqvist S, Stomrud E, Galasko D, Son SJ, Zetterberg H, Fortea J, Suárez-Calvet M, Jack CR Jr, Blennow K, Hansson O, Rosa-Neto P. Therriault J, et al. Among authors: karikari tk. Nat Aging. 2024 Nov;4(11):1529-1537. doi: 10.1038/s43587-024-00731-y. Epub 2024 Nov 12. Nat Aging. 2024. PMID: 39533113 Free PMC article.
Dementia risk reduction in the African context: Multi-national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa-FINGERS project).
Udeh-Momoh CT, Maina R, Anazodo UC, Akinyemi R, Atwoli L, Baker L, Bassil D, Blackmon K, Bosire E, Chemutai G, Crivelli L, Eze LU, Ibanez A, Kafetsouli D, Karikari TK, Khakali L, Kumar M, Lengyel I, de Jager Loots CA, Mangialasche F, Mbugua S, Merali Z, Mielke M, Mostert C, Muthoni E, Nesic-Taylor O, Ngugi A, Nguku S, Ogunniyi A, Ogunyemi A, Okonkwo OC, Okubadejo N, Perneczky R, Peto T, Riang'a RM, Saleh M, Sayed S, Shah J, Shah S, Solomon A, Thesen T, Trepel D, Ucheagwu V, Valcour V, Waa S, Watermeyer T, Yokoyama J, Zetterberg H, Kivipelto M; Africa‐FINGERS Study Team. Udeh-Momoh CT, et al. Among authors: karikari tk. Alzheimers Dement. 2024 Dec;20(12):8987-9003. doi: 10.1002/alz.14344. Epub 2024 Nov 7. Alzheimers Dement. 2024. PMID: 39511921 Free PMC article.
Plasma phosphorylated-tau217 is increased in Niemann-Pick disease type C.
Gonzalez-Ortiz F, Karikari TK, Taylor-Te Vruchte D, Shepherd D, Kirsebom BE, Fladby T, Platt F, Blennow K. Gonzalez-Ortiz F, et al. Among authors: karikari tk. Brain Commun. 2024 Oct 25;6(6):fcae375. doi: 10.1093/braincomms/fcae375. eCollection 2024. Brain Commun. 2024. PMID: 39502943 Free PMC article.
Where Do Plasma Biomarkers fit in With Current Alzheimer's Disease Detection?
Gildengers A, Weinstein AM, Gujral S, Zeng X, Diaz JL, Lafferty TK, Cowie M, Emanuel JE, Lopez O, Royse SK, Lopresti B, Karikari TK. Gildengers A, et al. Among authors: karikari tk. Am J Geriatr Psychiatry. 2024 Oct 1:S1064-7481(24)00478-0. doi: 10.1016/j.jagp.2024.09.015. Online ahead of print. Am J Geriatr Psychiatry. 2024. PMID: 39448295 Free article.
Plasma phosphorylated tau181 outperforms [18F] fluorodeoxyglucose positron emission tomography in the identification of early Alzheimer disease.
Quispialaya KM, Therriault J, Aliaga A, Tissot C, Servaes S, Rahmouni N, Karikari TK, Benedet AL, Ashton NJ, Macedo AC, Lussier FZ, Stevenson J, Wang YT, Arias JF, Hosseini A, Matsudaira T, Jean-Claude B, Gilfix BM, Zimmer ER, Soucy JP, Pascoal TA, Gauthier S, Zetterberg H, Blennow K, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative. Quispialaya KM, et al. Among authors: karikari tk. Eur J Neurol. 2024 Dec;31(12):e16255. doi: 10.1111/ene.16255. Epub 2024 Oct 24. Eur J Neurol. 2024. PMID: 39447157 Free PMC article.
171 results