Yi W - Search Results

1

Identification of Novel Organo-Se BTSA-Based Derivatives as Potent, Reversible, and Selective PPARγ Covalent Modulators for Antidiabetic Drug Discovery.

Chen F, Liu Q, Ma L, Yan C, Zhang H, Zhou Z, Yi W. Chen F, et al. Among authors: yi w. J Med Chem. 2024 Dec 20. doi: 10.1021/acs.jmedchem.4c02803. Online ahead of print. J Med Chem. 2024. PMID: 39705161

2

Structure-based screening and biological validation of the anti-thrombotic drug-dicoumarol as a novel and potent PPARγ-modulating ligand.

Ma L, Tang J, Cai G, Chen F, Liu Q, Zhou Z, Zhang S, Liu X, Hou N, Yi W. Ma L, et al. Among authors: yi w. Bioorg Chem. 2022 Dec;129:106191. doi: 10.1016/j.bioorg.2022.106191. Epub 2022 Oct 7. Bioorg Chem. 2022. PMID: 36270169

3

Structure-based screening, optimization and biological evaluation of novel chrysin-based derivatives as selective PPARγ modulators for the treatment of T2DM and hepatic steatosis.

Ma L, Tang J, Chen F, Liu Q, Huang J, Liu X, Zhou Z, Yi W. Ma L, et al. Among authors: yi w. Eur J Med Chem. 2024 Oct 5;276:116728. doi: 10.1016/j.ejmech.2024.116728. Epub 2024 Jul 30. Eur J Med Chem. 2024. PMID: 39089002

4

Identification and structural insight of an effective PPARγ modulator with improved therapeutic index for anti-diabetic drug discovery.

Jiang H, Zhou XE, Shi J, Zhou Z, Zhao G, Zhang X, Sun Y, Suino-Powell K, Ma L, Gao H, Yu X, Li J, Li J, Melcher K, Xu HE, Yi W. Jiang H, et al. Among authors: yi w. Chem Sci. 2020 Jan 21;11(8):2260-2268. doi: 10.1039/c9sc05487a. eCollection 2020 Feb 28. Chem Sci. 2020. PMID: 32190280 Free PMC article.

5

Identification of the anti-fungal drug fenticonazole nitrate as a novel PPARγ-modulating ligand with good therapeutic index: Structure-based screening and biological validation.

Ma L, Lian Y, Tang J, Chen F, Gao H, Zhou Z, Hou N, Yi W. Ma L, et al. Among authors: yi w. Pharmacol Res. 2021 Nov;173:105860. doi: 10.1016/j.phrs.2021.105860. Epub 2021 Aug 28. Pharmacol Res. 2021. PMID: 34461220

6

Chemodivergent assembly of ortho-functionalized phenols with tunable selectivity via rhodium(III)-catalyzed and solvent-controlled C-H activation.

Zhang H, Lin S, Gao H, Zhang K, Wang Y, Zhou Z, Yi W. Zhang H, et al. Among authors: yi w. Commun Chem. 2021 Jun 3;4(1):81. doi: 10.1038/s42004-021-00518-x. Commun Chem. 2021. PMID: 36697536 Free PMC article.

7

Identification of Novel PPARγ Partial Agonists Based on Virtual Screening Strategy: In Silico and In Vitro Experimental Validation.

Lian YE, Wang M, Ma L, Yi W, Liao S, Gao H, Zhou Z. Lian YE, et al. Among authors: yi w. Molecules. 2024 Oct 15;29(20):4881. doi: 10.3390/molecules29204881. Molecules. 2024. PMID: 39459249 Free PMC article.

8

Rh(III)-Catalyzed C-H Activation/Cycloisomerization of N-Phenoxyacetamides with Enynones for One-Pot Assembly of Furylated 2-Alkenylphenols.

Chen W, Liu FX, Bian M, Li L, Zhou Z, Yi W. Chen W, et al. Among authors: yi w. J Org Chem. 2019 Dec 6;84(23):15557-15566. doi: 10.1021/acs.joc.9b02534. Epub 2019 Nov 13. J Org Chem. 2019. PMID: 31682117

9

Rh(III)-Catalyzed Redox-Neutral [4+2] Annulation for Direct Assembly of 3-Acyl Isoquinolin-1(2H)-ones as Potent Antitumor Agents.

Bian M, Ma L, Wu M, Wu L, Gao H, Yi W, Zhang C, Zhou Z. Bian M, et al. Among authors: yi w. Chempluschem. 2020 Mar;85(3):405-410. doi: 10.1002/cplu.201900616. Epub 2019 Dec 11. Chempluschem. 2020. PMID: 32118370

10

Synthesis of Indenopyrazole Frameworks via Cascade C-H Functionalization/[3 + 2] Dipolar Cycloaddition/Aromatization Rearrangement Reactions.

Wu M, Wang R, Chen F, Chen W, Zhou Z, Yi W. Wu M, et al. Among authors: yi w. Org Lett. 2020 Sep 18;22(18):7152-7157. doi: 10.1021/acs.orglett.0c02506. Epub 2020 Aug 28. Org Lett. 2020. PMID: 32856454

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