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Page 1
Environmental exposure to common pesticide induces synaptic deficit and social memory impairment driven by neurodevelopmental vulnerability of hippocampal parvalbumin interneurons.
Di Re J, Koff L, Avchalumov Y, Singh AK, Baumgartner TJ, Marosi M, Matz LM, Hallberg LM, Ameredes BT, Seeley EH, Buffington SA, Green TA, Laezza F. Di Re J, et al. Among authors: laezza f. J Hazard Mater. 2024 Dec 16;485:136893. doi: 10.1016/j.jhazmat.2024.136893. Online ahead of print. J Hazard Mater. 2024. PMID: 39706027 Free article.
Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels.
Goetz R, Dover K, Laezza F, Shtraizent N, Huang X, Tchetchik D, Eliseenkova AV, Xu CF, Neubert TA, Ornitz DM, Goldfarb M, Mohammadi M. Goetz R, et al. Among authors: laezza f. J Biol Chem. 2009 Jun 26;284(26):17883-96. doi: 10.1074/jbc.M109.001842. Epub 2009 Apr 30. J Biol Chem. 2009. PMID: 19406745 Free PMC article.
The Nav1.2 channel is regulated by GSK3.
James TF, Nenov MN, Wildburger NC, Lichti CF, Luisi J, Vergara F, Panova-Electronova NI, Nilsson CL, Rudra JS, Green TA, Labate D, Laezza F. James TF, et al. Among authors: laezza f. Biochim Biophys Acta. 2015 Apr;1850(4):832-44. doi: 10.1016/j.bbagen.2015.01.011. Epub 2015 Jan 20. Biochim Biophys Acta. 2015. PMID: 25615535 Free PMC article.
CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability.
Hsu WC, Scala F, Nenov MN, Wildburger NC, Elferink H, Singh AK, Chesson CB, Buzhdygan T, Sohail M, Shavkunov AS, Panova NI, Nilsson CL, Rudra JS, Lichti CF, Laezza F. Hsu WC, et al. Among authors: laezza f. FASEB J. 2016 Jun;30(6):2171-86. doi: 10.1096/fj.201500161. Epub 2016 Feb 25. FASEB J. 2016. PMID: 26917740 Free PMC article.
These results suggest that a CK2-FGF14 axis may regulate Nav channels and neuronal excitability.-Hsu, W.-C. J., Scala, F., Nenov, M. N., Wildburger, N. C., Elferink, H., Singh, A. K., Chesson, C. B., Buzhdygan, T., Sohail, M., Shavkunov, A. ...I., Nilsson, C. L., Rudra, J. …
These results suggest that a CK2-FGF14 axis may regulate Nav channels and neuronal excitability.-Hsu, W.-C. J., Scala, F., Nenov, M. …
Consequences of acute Nav1.1 exposure to deltamethrin.
James TF, Nenov MN, Tapia CM, Lecchi M, Koshy S, Green TA, Laezza F. James TF, et al. Among authors: laezza f. Neurotoxicology. 2017 May;60:150-160. doi: 10.1016/j.neuro.2016.12.005. Epub 2016 Dec 19. Neurotoxicology. 2017. PMID: 28007400 Free PMC article.
84 results