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RNA sensing induced by chromosome missegregation augments anti-tumor immunity.
Sasaki N, Homme M, Murayama T, Osaki T, Tenma T, An T, Takegami Y, Tani T, Gedeon PC, Kobayashi Y, Cañadas I, Barbie DA, Yao R, Kitajima S. Sasaki N, et al. Among authors: murayama t. Mol Cell. 2024 Dec 10:S1097-2765(24)00950-X. doi: 10.1016/j.molcel.2024.11.025. Online ahead of print. Mol Cell. 2024. PMID: 39706184
Targeting TREX1 Induces Innate Immune Response in Drug-Resistant Small-Cell Lung Cancer.
Murayama T, Mahadevan NR, Meador CB, Ivanova EV, Pan Y, Knelson EH, Tani T, Nakayama J, Ma X, Thai TC, Hung YP, Kim W, Watanabe H, Cai KQ, Hata AN, Paweletz CP, Barbie DA, Cañadas I. Murayama T, et al. Cancer Res Commun. 2024 Sep 1;4(9):2399-2414. doi: 10.1158/2767-9764.CRC-24-0360. Cancer Res Commun. 2024. PMID: 39177280 Free PMC article.
Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.
Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigí M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Cañadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Jänne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA. Mahadevan NR, et al. Among authors: murayama t. Cancer Discov. 2021 Aug;11(8):1952-1969. doi: 10.1158/2159-8290.CD-20-0913. Epub 2021 Mar 11. Cancer Discov. 2021. PMID: 33707236 Free PMC article.
Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer.
Murayama T, Nakayama J, Jiang X, Miyata K, Morris AD, Cai KQ, Prasad RM, Ma X, Efimov A, Belani N, Gerstein ER, Tan Y, Zhou Y, Kim W, Maruyama R, Campbell KS, Chen L, Yang Y, Balachandran S, Cañadas I. Murayama T, et al. Cancer Discov. 2024 Mar 1;14(3):468-491. doi: 10.1158/2159-8290.CD-23-0486. Cancer Discov. 2024. PMID: 38189443 Free PMC article.
Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myeloma.
Hirano M, Imai Y, Kaito Y, Murayama T, Sato K, Ishida T, Yamamoto J, Ito T, Futami M, Ri M, Yasui H, Denda T, Tanaka Y, Ota Y, Nojima M, Kamikubo Y, Gotoh N, Iida S, Handa H, Tojo A. Hirano M, et al. Among authors: murayama t. J Exp Clin Cancer Res. 2021 Mar 23;40(1):110. doi: 10.1186/s13046-021-01909-7. J Exp Clin Cancer Res. 2021. PMID: 33757580 Free PMC article.
MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells.
Murayama T, Takeuchi Y, Yamawaki K, Natsume T, Li M, Marcela RN, Nishimura T, Kogure Y, Nakata A, Tominaga K, Sasahara A, Yano M, Ishikawa S, Ohta T, Ikeda K, Horie-Inoue K, Inoue S, Seki M, Suzuki Y, Sugano S, Enomoto T, Tanabe M, Tada KI, Kanemaki MT, Okamoto K, Tojo A, Gotoh N. Murayama T, et al. Cancer Sci. 2021 Mar;112(3):1209-1224. doi: 10.1111/cas.14776. Epub 2021 Jan 22. Cancer Sci. 2021. PMID: 33340428 Free PMC article.
Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells.
Tominaga K, Shimamura T, Kimura N, Murayama T, Matsubara D, Kanauchi H, Niida A, Shimizu S, Nishioka K, Tsuji EI, Yano M, Sugano S, Shimono Y, Ishii H, Saya H, Mori M, Akashi K, Tada KI, Ogawa T, Tojo A, Miyano S, Gotoh N. Tominaga K, et al. Among authors: murayama t. Oncogene. 2017 Mar 2;36(9):1276-1286. doi: 10.1038/onc.2016.293. Epub 2016 Aug 22. Oncogene. 2017. PMID: 27546618 Free PMC article.
Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Nishimura T, Nakata A, Chen X, Nishi K, Meguro-Horike M, Sasaki S, Kita K, Horike SI, Saitoh K, Kato K, Igarashi K, Murayama T, Kohno S, Takahashi C, Mukaida N, Yano S, Soga T, Tojo A, Gotoh N. Nishimura T, et al. Among authors: murayama t. Oncogene. 2019 Apr;38(14):2464-2481. doi: 10.1038/s41388-018-0589-1. Epub 2018 Dec 7. Oncogene. 2019. PMID: 30532069 Free PMC article.
1,176 results