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Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy.
Genome Biol. 2024 Dec 20;25(1):319. doi: 10.1186/s13059-024-03460-y.
Genome Biol. 2024.
PMID: 39707510
Free PMC article.
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia.
Hains AE, Uppal S, Cao JZ, Salwen HR, Applebaum MA, Cohn SL, Godley LA.
Hains AE, et al.
Epigenetics. 2022 Dec;17(13):2056-2074. doi: 10.1080/15592294.2022.2106078. Epub 2022 Aug 8.
Epigenetics. 2022.
PMID: 35942521
Free PMC article.
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Absence of SMARCB1 in rhabdoid tumor cells increases sensitivity to translation inhibition and alters translation efficiency of specific mRNAs.
Nguyen LT, Hains AE, Aziz-Zanjani MO, Dalsass M, Farooqee SBUD, Lu Y, Jackson PK, Van Rechem C.
Nguyen LT, et al. Among authors: hains ae.
J Biol Chem. 2024 Nov 13;300(12):107988. doi: 10.1016/j.jbc.2024.107988. Online ahead of print.
J Biol Chem. 2024.
PMID: 39542244
Free article.
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