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Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation.
Bogyo M, Upadhyay T, Woods E, Ahator S, Julin K, Faucher F, Hollander M, Pedowitz N, Abegg D, Hammond I, Eke I, Wang S, Chen S, Bennett J, Jo J, Lentz C, Adibekian A, Fellner M. Bogyo M, et al. Res Sq [Preprint]. 2024 Dec 13:rs.3.rs-5494070. doi: 10.21203/rs.3.rs-5494070/v1. Res Sq. 2024. PMID: 39711551 Free PMC article. Preprint.
An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor.
Wang S, Woods EC, Jo J, Zhu J, Hansel-Harris A, Holcomb M, Pedowitz NJ, Upadhyay T, Bennett J, Fellner M, Park KW, Zhang A, Valdez TA, Forli S, Chan AI, Cunningham CN, Bogyo M. Wang S, et al. Among authors: bogyo m. bioRxiv [Preprint]. 2024 Nov 8:2024.11.06.622387. doi: 10.1101/2024.11.06.622387. bioRxiv. 2024. PMID: 39574702 Free PMC article. Preprint.
Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of S. aureus Infections.
Jo J, Upadhyay T, Woods EC, Park KW, Pedowitz NJ, Jaworek-Korjakowska J, Wang S, Valdez TA, Fellner M, Bogyo M. Jo J, et al. Among authors: bogyo m. bioRxiv [Preprint]. 2023 Dec 12:2023.12.11.571116. doi: 10.1101/2023.12.11.571116. bioRxiv. 2023. Update in: J Am Chem Soc. 2024 Mar 13;146(10):6880-6892. doi: 10.1021/jacs.3c13974 PMID: 38168396 Free PMC article. Updated. Preprint.
Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets.
Bennett JM, Narwal SK, Kabeche S, Abegg D, Hackett F, Yeo T, Li VL, Muir RK, Faucher FF, Lovell S, Blackman MJ, Adibekian A, Yeh E, Fidock DA, Bogyo M. Bennett JM, et al. Among authors: bogyo m. bioRxiv [Preprint]. 2024 Jan 11:2024.01.11.575224. doi: 10.1101/2024.01.11.575224. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Sep 19;31(9):1714-1728.e10. doi: 10.1016/j.chembiol.2024.07.006 PMID: 38260474 Free PMC article. Updated. Preprint.
316 results