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Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis.
Luthra A, Montezuma-Rusca JM, La Vake CJ, LeDoyt M, Delgado KN, Davenport TC, Fiel-Gan M, Caimano MJ, Radolf JD, Hawley KL. Luthra A, et al. Among authors: hawley kl. PLoS Pathog. 2020 Sep 16;16(9):e1008871. doi: 10.1371/journal.ppat.1008871. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32936831 Free PMC article.
Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG+-Specific B-Cells in the Rabbit Model of Experimental Syphilis.
Delgado KN, Montezuma-Rusca JM, Orbe IC, Caimano MJ, La Vake CJ, Luthra A, Hennelly CM, Nindo FN, Meyer JW, Jones LD, Parr JB, Salazar JC, Moody MA, Radolf JD, Hawley KL. Delgado KN, et al. Among authors: hawley kl. mBio. 2022 Aug 30;13(4):e0163922. doi: 10.1128/mbio.01639-22. Epub 2022 Jul 12. mBio. 2022. PMID: 35862766 Free PMC article.
Use of Epivolve phage display to generate a monoclonal antibody with opsonic activity directed against a subdominant epitope on extracellular loop 4 of Treponema pallidum BamA (TP0326).
Ferguson MR, Delgado KN, McBride S, Orbe IC, La Vake CJ, Caimano MJ, Mendez Q, Moraes TF, Schryvers AB, Moody MA, Radolf JD, Weiner MP, Hawley KL. Ferguson MR, et al. Among authors: hawley kl. Front Immunol. 2023 Aug 22;14:1222267. doi: 10.3389/fimmu.2023.1222267. eCollection 2023. Front Immunol. 2023. PMID: 37675118 Free PMC article.
Sequence Variation of Rare Outer Membrane Protein β-Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp. pallidum, the Syphilis Spirochete.
Kumar S, Caimano MJ, Anand A, Dey A, Hawley KL, LeDoyt ME, La Vake CJ, Cruz AR, Ramirez LG, Paštěková L, Bezsonova I, Šmajs D, Salazar JC, Radolf JD. Kumar S, et al. Among authors: hawley kl. mBio. 2018 Jun 12;9(3):e01006-18. doi: 10.1128/mBio.01006-18. mBio. 2018. PMID: 29895642 Free PMC article.
50 results