Wedell A - Search Results

1

Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster.

El Fissi N, Rosenberger FA, Chang K, Wilhalm A, Barton-Owen T, Hansen FM, Golder Z, Alsina D, Wedell A, Mann M, Chinnery PF, Freyer C, Wredenberg A. El Fissi N, et al. Among authors: wedell a. Nat Commun. 2024 Dec 23;15(1):10719. doi: 10.1038/s41467-024-55559-2. Nat Commun. 2024. PMID: 39715749 Free PMC article.

2

SUV3 helicase is required for correct processing of mitochondrial transcripts.

Clemente P, Pajak A, Laine I, Wibom R, Wedell A, Freyer C, Wredenberg A. Clemente P, et al. Among authors: wedell a. Nucleic Acids Res. 2015 Sep 3;43(15):7398-413. doi: 10.1093/nar/gkv692. Epub 2015 Jul 7. Nucleic Acids Res. 2015. PMID: 26152302 Free PMC article.

3

Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation.

Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A. Bratic A, et al. Among authors: wedell a. PLoS Genet. 2016 May 13;12(5):e1006028. doi: 10.1371/journal.pgen.1006028. eCollection 2016 May. PLoS Genet. 2016. PMID: 27176048 Free PMC article.

4

A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.

Siibak T, Clemente P, Bratic A, Bruhn H, Kauppila TES, Macao B, Schober FA, Lesko N, Wibom R, Naess K, Nennesmo I, Wedell A, Peter B, Freyer C, Falkenberg M, Wredenberg A. Siibak T, et al. Among authors: wedell a. Hum Mol Genet. 2017 Jul 1;26(13):2515-2525. doi: 10.1093/hmg/ddx146. Hum Mol Genet. 2017. PMID: 28430993 Free PMC article.

5

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo.

Pajak A, Laine I, Clemente P, El-Fissi N, Schober FA, Maffezzini C, Calvo-Garrido J, Wibom R, Filograna R, Dhir A, Wedell A, Freyer C, Wredenberg A. Pajak A, et al. Among authors: wedell a. PLoS Genet. 2019 Jul 31;15(7):e1008240. doi: 10.1371/journal.pgen.1008240. eCollection 2019 Jul. PLoS Genet. 2019. PMID: 31365523 Free PMC article.

6

FBXL4 deficiency increases mitochondrial removal by autophagy.

Alsina D, Lytovchenko O, Schab A, Atanassov I, Schober FA, Jiang M, Koolmeister C, Wedell A, Taylor RW, Wredenberg A, Larsson NG. Alsina D, et al. Among authors: wedell a. EMBO Mol Med. 2020 Jul 7;12(7):e11659. doi: 10.15252/emmm.201911659. Epub 2020 Jun 11. EMBO Mol Med. 2020. PMID: 32525278 Free PMC article.

7

Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits.

Rosenberger FA, Atanassov I, Moore D, Calvo-Garrido J, Moedas MF, Wedell A, Freyer C, Wredenberg A. Rosenberger FA, et al. Among authors: wedell a. Mol Cell Proteomics. 2021;20:100065. doi: 10.1016/j.mcpro.2021.100065. Epub 2021 Feb 25. Mol Cell Proteomics. 2021. PMID: 33640490 Free PMC article.

8

Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy.

Gineste C, Hernandez A, Ivarsson N, Cheng AJ, Naess K, Wibom R, Lesko N, Bruhn H, Wedell A, Freyer C, Zhang SJ, Carlström M, Lanner JT, Andersson DC, Bruton JD, Wredenberg A, Westerblad H. Gineste C, et al. Among authors: wedell a. Hum Mol Genet. 2015 Dec 1;24(23):6580-7. doi: 10.1093/hmg/ddv361. Epub 2015 Sep 14. Hum Mol Genet. 2015. PMID: 26374844 Free PMC article.

9

RNA modification landscape of the human mitochondrial tRNA^Lys regulates protein synthesis.

Richter U, Evans ME, Clark WC, Marttinen P, Shoubridge EA, Suomalainen A, Wredenberg A, Wedell A, Pan T, Battersby BJ. Richter U, et al. Among authors: wedell a. Nat Commun. 2018 Sep 27;9(1):3966. doi: 10.1038/s41467-018-06471-z. Nat Commun. 2018. PMID: 30262910 Free PMC article.

10

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.

Olivé M, Engvall M, Ravenscroft G, Cabrera-Serrano M, Jiao H, Bortolotti CA, Pignataro M, Lambrughi M, Jiang H, Forrest ARR, Benseny-Cases N, Hofbauer S, Obinger C, Battistuzzi G, Bellei M, Borsari M, Di Rocco G, Viola HM, Hool LC, Cladera J, Lagerstedt-Robinson K, Xiang F, Wredenberg A, Miralles F, Baiges JJ, Malfatti E, Romero NB, Streichenberger N, Vial C, Claeys KG, Straathof CSM, Goris A, Freyer C, Lammens M, Bassez G, Kere J, Clemente P, Sejersen T, Udd B, Vidal N, Ferrer I, Edström L, Wedell A, Laing NG. Olivé M, et al. Among authors: wedell a. Nat Commun. 2019 Mar 27;10(1):1396. doi: 10.1038/s41467-019-09111-2. Nat Commun. 2019. PMID: 30918256 Free PMC article.

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