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Page 1
Thoughts for the future.
Alkhalaf LM, Arrowsmith C, Balskus EP, Bergamini G, Bhandari R, Chang CJ, Chen P, Chen X, Ciulli A, Cricco JA, Davis BG, Delbianco M, Dudareva N, Dueber E, Ferguson F, de Giuseppe PO, Hamachi I, Hammond MC, Hatzios SK, Do Heo W, Janet JP, Kamat SS, Knapp S, Krishnan Y, Lang K, Laraia L, Leveson-Gower RB, Li XD, Liu DR, Liu MF, London N, Mahanta N, Mayor-Ruiz C, Muir T, Murakami MT, Rhee HW, Robers M, Satz A, Schulman BA, Shen B, Shoichet B, Strauss E, Suzuki T, Tiwary P, Waldmann H, Ward TR, Weeks A, Weerapana E, Winter G. Alkhalaf LM, et al. Among authors: waldmann h. Nat Chem Biol. 2025 Jan;21(1):6-15. doi: 10.1038/s41589-024-01802-2. Nat Chem Biol. 2025. PMID: 39719500 No abstract available.
Identification of readily available pseudo-natural products.
Pahl A, Grygorenko OO, Kondratov IS, Waldmann H. Pahl A, et al. Among authors: waldmann h. RSC Med Chem. 2024 Jul 4;15(8):2709-2717. doi: 10.1039/d4md00310a. eCollection 2024 Aug 14. RSC Med Chem. 2024. PMID: 39149091 Free PMC article.
Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3.
Hennes E, Lucas B, Scholes NS, Cheng XF, Scott DC, Bischoff M, Reich K, Gasper R, Lucas M, Xu TT, Pulvermacher LM, Dötsch L, Imrichova H, Brause A, Naredla KR, Sievers S, Kumar K, Janning P, Gersch M, Murray PJ, Schulman BA, Winter GE, Ziegler S, Waldmann H. Hennes E, et al. Among authors: waldmann h. bioRxiv [Preprint]. 2024 Jul 13:2024.07.10.602857. doi: 10.1101/2024.07.10.602857. bioRxiv. 2024. PMID: 39026748 Free PMC article. Preprint.
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP.
Cigler M, Imrichova H, Frommelt F, Caramelle L, Depta L, Rukavina A, Kagiou C, Hannich JT, Mayor-Ruiz C, Superti-Furga G, Sievers S, Forrester A, Laraia L, Waldmann H, Winter GE. Cigler M, et al. Among authors: waldmann h. Nat Chem Biol. 2024 Jun 21. doi: 10.1038/s41589-024-01614-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38907113
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.
Patil S, Cremosnik G, Dötsch L, Flegel J, Schulte B, Maier KC, Žumer K, Cramer P, Janning P, Sievers S, Ziegler S, Waldmann H. Patil S, et al. Among authors: waldmann h. Angew Chem Int Ed Engl. 2024 Aug 5;63(32):e202404645. doi: 10.1002/anie.202404645. Epub 2024 Jul 4. Angew Chem Int Ed Engl. 2024. PMID: 38801173
1,031 results