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Editorial: DNA Replication Stress and Cell Fate.
Deng L, Chen CL, Zhai Y, Dong Y, Lou H. Deng L, et al. Among authors: chen cl. Front Cell Dev Biol. 2021 Oct 25;9:778486. doi: 10.3389/fcell.2021.778486. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34760895 Free PMC article. No abstract available.
Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome.
Chakraborty A, Jenjaroenpun P, Li J, El Hilali S, McCulley A, Haarer B, Hoffman EA, Belak A, Thorland A, Hehnly H, Schildkraut CL, Chen CL, Kuznetsov VA, Feng W. Chakraborty A, et al. Among authors: chen cl. Cell Rep. 2020 Sep 22;32(12):108179. doi: 10.1016/j.celrep.2020.108179. Cell Rep. 2020. PMID: 32966779 Free PMC article.
The human pre-replication complex is an open complex.
Li J, Dong J, Wang W, Yu D, Fan X, Hui YC, Lee CSK, Lam WH, Alary N, Yang Y, Zhang Y, Zhao Q, Chen CL, Tye BK, Dang S, Zhai Y. Li J, et al. Among authors: chen cl. Cell. 2023 Jan 5;186(1):98-111.e21. doi: 10.1016/j.cell.2022.12.008. Cell. 2023. PMID: 36608662 Free article.
OKseqHMM: a genome-wide replication fork directionality analysis toolkit.
Liu Y, Wu X, d'Aubenton-Carafa Y, Thermes C, Chen CL. Liu Y, et al. Among authors: chen cl. Nucleic Acids Res. 2023 Feb 28;51(4):e22. doi: 10.1093/nar/gkac1239. Nucleic Acids Res. 2023. PMID: 36629249 Free PMC article.
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/CL-CHEN-Lab/OK-Seq, https://doi.org/10.5281/zenodo.7428883). Then, we used OKseqHMM to analyse a large number of datasets obtained …
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/C …
4,561 results