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The pathogenic T42A mutation in SHP2 rewires the interaction specificity of its N-terminal regulatory domain.
van Vlimmeren AE, Voleti R, Chartier CA, Jiang Z, Karandur D, Humphries PA, Lo WL, Shah NH. van Vlimmeren AE, et al. Among authors: chartier ca. bioRxiv [Preprint]. 2024 Apr 9:2023.07.10.548257. doi: 10.1101/2023.07.10.548257. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2407159121. doi: 10.1073/pnas.2407159121 PMID: 37502916 Free PMC article. Updated. Preprint.