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Page 1
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis.
Diehl C, Soberón V, Baygün S, Chu Y, Mandelbaum J, Kraus L, Engleitner T, Rudelius M, Fangazio M, Daniel C, Bortoluzzi S, Helmrath S, Singroul P, Gölling V, Osorio Barrios F, Seyhan G, Oßwald L, Kober-Hasslacher M, Zeng T, Öllinger R, Afzali AM, Korn T, Honarpisheh M, Lech M, Ul Ain Q, Pircher J, Imširović V, Jelenčić V, Wensveen FM, Passerini V, Bärthel S, Bhagat G, Dominguez-Sola D, Saur D, Steiger K, Rad R, Pasqualucci L, Weigert O, Schmidt-Supprian M. Diehl C, et al. Among authors: ollinger r. Immunity. 2024 Dec 25:S1074-7613(24)00538-7. doi: 10.1016/j.immuni.2024.11.023. Online ahead of print. Immunity. 2024. PMID: 39729992 Free article.
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling.
Bortoluzzi S, Dashtsoodol N, Engleitner T, Drees C, Helmrath S, Mir J, Toska A, Flossdorf M, Öllinger R, Solovey M, Colomé-Tatché M, Kalfaoglu B, Ono M, Buch T, Ammon T, Rad R, Schmidt-Supprian M. Bortoluzzi S, et al. Among authors: ollinger r. Immunity. 2021 Nov 9;54(11):2497-2513.e9. doi: 10.1016/j.immuni.2021.09.003. Epub 2021 Sep 24. Immunity. 2021. PMID: 34562377 Free article.
IL-24 intrinsically regulates Th17 cell pathogenicity in mice.
Sie C, Kant R, Peter C, Muschaweckh A, Pfaller M, Nirschl L, Moreno HD, Chadimová T, Lepennetier G, Kuhlmann T, Öllinger R, Engleitner T, Rad R, Korn T. Sie C, et al. Among authors: ollinger r. J Exp Med. 2022 Aug 1;219(8):e20212443. doi: 10.1084/jem.20212443. Epub 2022 Jul 12. J Exp Med. 2022. PMID: 35819408 Free PMC article.
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Among authors: ollinger r. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.
Genome-scale pan-cancer interrogation of lncRNA dependencies using CasRx.
Montero JJ, Trozzo R, Sugden M, Öllinger R, Belka A, Zhigalova E, Waetzig P, Engleitner T, Schmidt-Supprian M, Saur D, Rad R. Montero JJ, et al. Among authors: ollinger r. Nat Methods. 2024 Apr;21(4):584-596. doi: 10.1038/s41592-024-02190-0. Epub 2024 Feb 26. Nat Methods. 2024. PMID: 38409225 Free PMC article.
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Wartewig T, Kurgyis Z, Keppler S, Pechloff K, Hameister E, Öllinger R, Maresch R, Buch T, Steiger K, Winter C, Rad R, Ruland J. Wartewig T, et al. Among authors: ollinger r. Nature. 2017 Dec 7;552(7683):121-125. doi: 10.1038/nature24649. Epub 2017 Nov 15. Nature. 2017. PMID: 29143824 Free PMC article.
RIG-I activation is critical for responsiveness to checkpoint blockade.
Heidegger S, Wintges A, Stritzke F, Bek S, Steiger K, Koenig PA, Göttert S, Engleitner T, Öllinger R, Nedelko T, Fischer JC, Makarov V, Winter C, Rad R, van den Brink MRM, Ruland J, Bassermann F, Chan TA, Haas T, Poeck H. Heidegger S, et al. Among authors: ollinger r. Sci Immunol. 2019 Sep 13;4(39):eaau8943. doi: 10.1126/sciimmunol.aau8943. Sci Immunol. 2019. PMID: 31519811
Mir34a constrains pancreatic carcinogenesis.
Hidalgo-Sastre A, Lubeseder-Martellato C, Engleitner T, Steiger K, Zhong S, Desztics J, Öllinger R, Rad R, Schmid RM, Hermeking H, Siveke JT, von Figura G. Hidalgo-Sastre A, et al. Among authors: ollinger r. Sci Rep. 2020 Jun 15;10(1):9654. doi: 10.1038/s41598-020-66561-1. Sci Rep. 2020. PMID: 32541781 Free PMC article.
The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans.
Mitsdoerffer M, Aly L, Barz M, Engleitner T, Sie C, Delbridge C, Lepennetier G, Öllinger R, Pfaller M, Wiestler B, Rad R, Meyer B, Knier B, Schmidt-Graf F, Gempt J, Korn T. Mitsdoerffer M, et al. Among authors: ollinger r. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206208119. doi: 10.1073/pnas.2206208119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969754 Free PMC article.
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Griger J, Widholz SA, Jesinghaus M, de Andrade Krätzig N, Lange S, Engleitner T, Montero JJ, Zhigalova E, Öllinger R, Suresh V, Winkler W, Lier S, Baranov O, Trozzo R, Ben Khaled N, Chakraborty S, Yu J, Konukiewitz B, Steiger K, Pfarr N, Rajput A, Sailer D, Keller G, Schirmacher P, Röcken C, Fagerstedt KW, Mayerle J, Schmidt-Supprian M, Schneider G, Weichert W, Calado DP, Sommermann T, Klöppel G, Rajewsky K, Saur D, Rad R. Griger J, et al. Among authors: ollinger r. Cancer Cell. 2023 Jul 10;41(7):1327-1344.e10. doi: 10.1016/j.ccell.2023.06.001. Epub 2023 Jun 22. Cancer Cell. 2023. PMID: 37352862 Free article.
230 results