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Discovery of novel bicyclic and tricyclic cyclohepta[b]thiophene derivatives as multipotent AChE and BChE inhibitors, in-Vivo and in-Vitro assays, ADMET and molecular docking simulation.
Fayed EA, El-Sebaey SA, Ebrahim MA, Abu-Elfotuh K, El-Sayed Mansour R, Mohamed EK, Hamdan AME, Al-Subaie FT, Albalawi GS, Albalawi TM, Hamdan AM, Mohammed AA, Ramsis TM. Fayed EA, et al. Among authors: mohammed aa. Eur J Med Chem. 2024 Dec 24;284:117201. doi: 10.1016/j.ejmech.2024.117201. Online ahead of print. Eur J Med Chem. 2024. PMID: 39731791 Free article.
Fluoxetine ameliorates Alzheimer's disease progression and prevents the exacerbation of cardiovascular dysfunction of socially isolated depressed rats through activation of Nrf2/HO-1 and hindering TLR4/NLRP3 inflammasome signaling pathway.
Abu-Elfotuh K, Al-Najjar AH, Mohammed AA, Aboutaleb AS, Badawi GA. Abu-Elfotuh K, et al. Among authors: mohammed aa. Int Immunopharmacol. 2022 Mar;104:108488. doi: 10.1016/j.intimp.2021.108488. Epub 2022 Jan 15. Int Immunopharmacol. 2022. PMID: 35042170
The consumption pattern and perception of using artificial sweeteners among the public in Tabuk region, Saudi Arabia.
Alharthi SAS, Alaisayi KHA, Alalawi LYS, Alamri ROS, Abu-Elfotuh K, Alenazi TS, Amirthalingam P, Albariqi HAH, Mohammed AA, Alsubayti N, Hamdan AME, Kozman MR. Alharthi SAS, et al. Among authors: mohammed aa. Front Public Health. 2023 Jun 22;11:1166868. doi: 10.3389/fpubh.2023.1166868. eCollection 2023. Front Public Health. 2023. PMID: 37427264 Free PMC article.
Neuroprotective Effects of Some Nutraceuticals against Manganese-Induced Parkinson's Disease in Rats: Possible Modulatory Effects on TLR4/NLRP3/NF-κB, GSK-3β, Nrf2/HO-1, and Apoptotic Pathways.
Abu-Elfotuh K, Hamdan AME, Mohammed AA, Atwa AM, Kozman MR, Ibrahim AM, Motawea SM, Selim HMRM, Tohamy STK, Nour El-Din M, Zaghlool SS, Gowifel AMH, Awny MM. Abu-Elfotuh K, et al. Among authors: mohammed aa. Pharmaceuticals (Basel). 2022 Dec 14;15(12):1554. doi: 10.3390/ph15121554. Pharmaceuticals (Basel). 2022. PMID: 36559006 Free PMC article.
Pramipexole and Lactoferrin ameliorate Cyclophosphamide-Induced haemorrhagic cystitis via targeting Sphk1/S1P/MAPK, TLR-4/NF-κB, and NLRP3/caspase-1/IL-1β signalling pathways and modulating the Nrf2/HO-1 pathway.
Abdel Baky NA, Al-Najjar AH, Elariny HA, Sallam AS, Mohammed AA. Abdel Baky NA, et al. Among authors: mohammed aa. Int Immunopharmacol. 2022 Nov;112:109282. doi: 10.1016/j.intimp.2022.109282. Epub 2022 Oct 3. Int Immunopharmacol. 2022. PMID: 36194984
522 results