Zheng X - Search Results

1

Discovery of novel xanthohumol C derivatives regulating XRCC2 transcription and expression for the treatment of colorectal cancer.

Zhu Q, Wang M, Wang Y, Li B, Zheng J, Hu Y, Shi C, Wang D, Cao D, Liu Z, Zheng X, Wang K. Zhu Q, et al. Among authors: zheng j, zheng x. Bioorg Med Chem. 2025 Feb 1;118:118048. doi: 10.1016/j.bmc.2024.118048. Epub 2024 Dec 19. Bioorg Med Chem. 2025. PMID: 39731930

2

Discovery of pyrimidine-2,4-diamine analogues as efficiency anticancer drug by targeting GTSE1.

Xing S, Yang H, Chen X, Wang Y, Zhang S, Wang P, Chen C, Wang K, Liu Z, Zheng X. Xing S, et al. Among authors: zheng x. Bioorg Chem. 2024 Oct;151:107700. doi: 10.1016/j.bioorg.2024.107700. Epub 2024 Aug 8. Bioorg Chem. 2024. PMID: 39128245

3

Discovery of β-cyclocitral-derived mono-carbonyl curcumin analogs as anti-hepatocellular carcinoma agents via suppression of MAPK signaling pathway.

Han H, Alsayed AMM, Wang Y, Yan Q, Shen A, Zhang J, Ye Y, Liu Z, Wang K, Zheng X. Han H, et al. Among authors: zheng x. Bioorg Chem. 2023 Mar;132:106358. doi: 10.1016/j.bioorg.2023.106358. Epub 2023 Jan 10. Bioorg Chem. 2023. PMID: 36642021

4

Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells.

Qiu YD, Yan Q, Wang Y, Ye YF, Wang Y, Wang MY, Wang PP, Zhang SY, Wang DL, Yan H, Ruan J, Zhao YJ, Huang LH, Cho N, Wang K, Zheng XH, Liu ZG. Qiu YD, et al. Acta Pharmacol Sin. 2024 Jun;45(6):1276-1286. doi: 10.1038/s41401-024-01243-6. Epub 2024 Mar 4. Acta Pharmacol Sin. 2024. PMID: 38438580

5

Synthesis and biological evaluation of novel N-substituted benzamides as anti-migration agents for treatment of osteosarcoma.

Chen X, Wang G, Mohammed Alsayed AM, Du Z, Lu Liu, Ma Y, Liu P, Zhang Q, Chen X, Chen W, Ye F, Zheng X, Liu Z. Chen X, et al. Among authors: zheng x. Eur J Med Chem. 2021 Mar 15;214:113203. doi: 10.1016/j.ejmech.2021.113203. Epub 2021 Jan 24. Eur J Med Chem. 2021. PMID: 33530028

6

Design, synthesis, and biological evaluation of indazole derivatives as selective and potent FGFR4 inhibitors for the treatment of FGF19-driven hepatocellular cancer.

Chen X, Liu Y, Zhang L, Chen D, Dong Z, Zhao C, Liu Z, Xia Q, Wu J, Chen Y, Zheng X, Cai Y. Chen X, et al. Among authors: zheng x. Eur J Med Chem. 2021 Mar 15;214:113219. doi: 10.1016/j.ejmech.2021.113219. Epub 2021 Jan 29. Eur J Med Chem. 2021. PMID: 33618175

7

Discovery of Potent and Orally Bioavailable Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for the Treatment of Osteosarcoma.

Chen X, Liu L, Liu P, Chen Y, Lin D, Yan H, Yan Q, Wang Y, Qiu Y, Fang B, Huang H, Qian J, Zhao Y, Du Z, Zhang Q, Li X, Zheng X, Liu Z. Chen X, et al. Among authors: zheng x. J Med Chem. 2022 Apr 14;65(7):5374-5391. doi: 10.1021/acs.jmedchem.1c01732. Epub 2022 Mar 3. J Med Chem. 2022. PMID: 35239349

8

Author Correction: Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells.

Qiu YD, Yan Q, Wang Y, Ye YF, Wang Y, Wang MY, Wang PP, Zhang SY, Wang DL, Yan H, Ruan J, Zhao YJ, Huang LH, Cho N, Wang K, Zheng XH, Liu ZG. Qiu YD, et al. Acta Pharmacol Sin. 2024 Aug 28. doi: 10.1038/s41401-024-01370-0. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 39198664 No abstract available.

9

cyy-287, a novel pyrimidine-2,4-diamine derivative, inhibits tumor growth of EGFR-driven non-small cell lung cancer via the ERK pathway.

Zhang Q, Huang H, Zheng S, Tang Y, Zhang X, Zhu Q, Ni Z, Zheng X, Wang K, Huang L, Zhao Y, Liu Z, Qian J. Zhang Q, et al. Among authors: zheng s, zheng x. Acta Biochim Biophys Sin (Shanghai). 2022 Oct 25;54(10):1540-1551. doi: 10.3724/abbs.2022139. Acta Biochim Biophys Sin (Shanghai). 2022. PMID: 36239356 Free PMC article.

10

Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.

Zhang DF, Yang ZC, Chen JQ, Jin XX, Qiu YD, Chen XJ, Shi HY, Liu ZG, Wang MS, Liang G, Zheng XH. Zhang DF, et al. BMC Complement Med Ther. 2021 Jul 6;21(1):195. doi: 10.1186/s12906-021-03369-0. BMC Complement Med Ther. 2021. PMID: 34229670 Free PMC article.

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