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Page 1
BET inhibitor JQ1 induces apoptosis of ovarian and endometrial endometrioid carcinoma cells by downregulating c‑Myc.
Tanimoto S, Sone K, Jonouchi Y, Hachijo R, Suzuki E, Tsuboyama N, Toyohara Y, Inoue F, Honjoh H, Fukuda T, Taguchi A, Miyamoto Y, Iriyama T, Mori M, Asada K, Komatsu M, Kaneko S, Hamamoto R, Wada-Hiraike O, Oda K, Hirota Y, Osuga Y. Tanimoto S, et al. Among authors: hamamoto r. Oncol Lett. 2024 Dec 19;29(3):106. doi: 10.3892/ol.2024.14852. eCollection 2025 Mar. Oncol Lett. 2024. PMID: 39736925 Free PMC article.
Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer.
Oki S, Sone K, Oda K, Hamamoto R, Ikemura M, Maeda D, Takeuchi M, Tanikawa M, Mori-Uchino M, Nagasaka K, Miyasaka A, Kashiyama T, Ikeda Y, Arimoto T, Kuramoto H, Wada-Hiraike O, Kawana K, Fukayama M, Osuga Y, Fujii T. Oki S, et al. Among authors: hamamoto r. Oncotarget. 2017 Jun 20;8(25):40402-40411. doi: 10.18632/oncotarget.16316. Oncotarget. 2017. PMID: 28418882 Free PMC article.
Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.
Kukita A, Sone K, Oda K, Hamamoto R, Kaneko S, Komatsu M, Wada M, Honjoh H, Kawata Y, Kojima M, Oki S, Sato M, Asada K, Taguchi A, Miyasaka A, Tanikawa M, Nagasaka K, Matsumoto Y, Wada-Hiraike O, Osuga Y, Fujii T. Kukita A, et al. Among authors: hamamoto r. Biochem Biophys Res Commun. 2019 May 28;513(2):340-346. doi: 10.1016/j.bbrc.2019.03.155. Epub 2019 Apr 4. Biochem Biophys Res Commun. 2019. PMID: 30955858
The histone methyltransferase WHSC1 is regulated by EZH2 and is important for ovarian clear cell carcinoma cell proliferation.
Kojima M, Sone K, Oda K, Hamamoto R, Kaneko S, Oki S, Kukita A, Machino H, Honjoh H, Kawata Y, Kashiyama T, Asada K, Tanikawa M, Mori-Uchino M, Tsuruga T, Nagasaka K, Matsumoto Y, Wada-Hiraike O, Osuga Y, Fujii T. Kojima M, et al. Among authors: hamamoto r. BMC Cancer. 2019 May 15;19(1):455. doi: 10.1186/s12885-019-5638-9. BMC Cancer. 2019. PMID: 31092221 Free PMC article.
Genomic alterations in STK11 can predict clinical outcomes in cervical cancer patients.
Hirose S, Murakami N, Takahashi K, Kuno I, Takayanagi D, Asami Y, Matsuda M, Shimada Y, Yamano S, Sunami K, Yoshida K, Honda T, Nakahara T, Watanabe T, Komatsu M, Hamamoto R, Kato MK, Matsumoto K, Okuma K, Kuroda T, Okamoto A, Itami J, Kohno T, Kato T, Shiraishi K, Yoshida H. Hirose S, et al. Among authors: hamamoto r. Gynecol Oncol. 2020 Jan;156(1):203-210. doi: 10.1016/j.ygyno.2019.10.022. Epub 2019 Nov 19. Gynecol Oncol. 2020. PMID: 31757465
193 results