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Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage.
Ilnytska O, Lai K, Gorshkov K, Schultz ML, Tran BN, Jeziorek M, Kunkel TJ, Azaria RD, McLoughlin HS, Waghalter M, Xu Y, Schlame M, Altan-Bonnet N, Zheng W, Lieberman AP, Dobrowolski R, Storch J. Ilnytska O, et al. Among authors: waghalter m. J Biol Chem. 2021 Jul;297(1):100813. doi: 10.1016/j.jbc.2021.100813. Epub 2021 May 21. J Biol Chem. 2021. PMID: 34023384 Free PMC article.