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Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.
Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL. Kenwood BM, et al. Among authors: hoehn kl. Mol Metab. 2013 Nov 28;3(2):114-23. doi: 10.1016/j.molmet.2013.11.005. eCollection 2014 Apr. Mol Metab. 2013. PMID: 24634817 Free PMC article.
Dietary sugar intake increases liver tumor incidence in female mice.
Healy ME, Lahiri S, Hargett SR, Chow JD, Byrne FL, Breen DS, Kenwood BM, Taddeo EP, Lackner C, Caldwell SH, Hoehn KL. Healy ME, et al. Among authors: hoehn kl. Sci Rep. 2016 Feb 29;6:22292. doi: 10.1038/srep22292. Sci Rep. 2016. PMID: 26924712 Free PMC article.
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress.
Byrne FL, Olzomer EM, Marriott GR, Quek LE, Katen A, Su J, Nelson ME, Hart-Smith G, Larance M, Sebesfi VF, Cuff J, Martyn GE, Childress E, Alexopoulos SJ, Poon IK, Faux MC, Burgess AW, Reid G, McCarroll JA, Santos WL, Quinlan KG, Turner N, Fazakerley DJ, Kumar N, Hoehn KL. Byrne FL, et al. Among authors: hoehn kl. Redox Biol. 2020 Jan;28:101374. doi: 10.1016/j.redox.2019.101374. Epub 2019 Nov 5. Redox Biol. 2020. PMID: 31743887 Free PMC article.
105 results