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Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy.
Ediriweera GR, Sivaram AJ, Cowin G, Brown ML, McAlary L, Lum JS, Fletcher NL, Robinson L, Simpson JD, Chen L, Wasielewska JM, Byrne E, Finnie JW, Manavis J, White AR, Yerbury JJ, Thurecht KJ, Vine KL. Ediriweera GR, et al. Among authors: cowin g. J Control Release. 2024 Dec 12;378:221-235. doi: 10.1016/j.jconrel.2024.11.074. Online ahead of print. J Control Release. 2024. PMID: 39645085 Free article.
Multifunctional Fluoropolymer-Engineered Magnetic Nanoparticles to Facilitate Blood-Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma.
Forgham H, Zhu J, Huang X, Zhang C, Biggs H, Liu L, Wang YC, Fletcher N, Humphries J, Cowin G, Mardon K, Kavallaris M, Thurecht K, Davis TP, Qiao R. Forgham H, et al. Among authors: cowin g. Adv Sci (Weinh). 2024 Jul;11(25):e2401340. doi: 10.1002/advs.202401340. Epub 2024 Apr 22. Adv Sci (Weinh). 2024. PMID: 38647396 Free PMC article.
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands.
Kallinen A, Mardon K, Lane S, Montgomery AP, Bhalla R, Stimson DHR, Ahamed M, Cowin GJ, Hibbs D, Werry EL, Fulton R, Connor M, Kassiou M. Kallinen A, et al. Among authors: cowin gj. ACS Chem Neurosci. 2023 Aug 16;14(16):2902-2921. doi: 10.1021/acschemneuro.3c00345. Epub 2023 Jul 27. ACS Chem Neurosci. 2023. PMID: 37499194
Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/β-Hydrolase Domain 6 (ABHD6).
Mardon K, Patel JZ, Savinainen JR, Stimson DHR, Oyagawa CRM, Grimsey NL, Migotto MA, Njiru GFM, Hamilton BR, Cowin G, Yli-Kauhaluoma J, Vanduffel W, Blakey I, Bhalla R, Cawthorne C, Celen S, Bormans G, Thurecht KJ, Ahamed M. Mardon K, et al. Among authors: cowin g. J Med Chem. 2023 Jan 12;66(1):538-552. doi: 10.1021/acs.jmedchem.2c01485. Epub 2022 Dec 14. J Med Chem. 2023. PMID: 36516997
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption.
Janowicz PW, Houston ZH, Bunt J, Fletcher NL, Bell CA, Cowin G, Howard CB, Taslima D, Westra van Holthe N, Prior A, Soh V, Ghosh S, Humphries J, Huda P, Mahler SM, Richards LJ, Thurecht KJ. Janowicz PW, et al. Among authors: cowin g. Biomaterials. 2022 Apr;283:121416. doi: 10.1016/j.biomaterials.2022.121416. Epub 2022 Feb 17. Biomaterials. 2022. PMID: 35217483
106 results