Wehrle E - Search Results

1

Spatial transcriptomics in bone mechanomics: Exploring the mechanoregulation of fracture healing in the era of spatial omics.

Mathavan N, Singh A, Marques FC, Günther D, Kuhn GA, Wehrle E, Müller R. Mathavan N, et al. Among authors: wehrle e. Sci Adv. 2025 Jan 3;11(1):eadp8496. doi: 10.1126/sciadv.adp8496. Epub 2025 Jan 1. Sci Adv. 2025. PMID: 39742473 Free PMC article.

2

The association between mineralised tissue formation and the mechanical local in vivo environment: Time-lapsed quantification of a mouse defect healing model.

Tourolle Né Betts DC, Wehrle E, Paul GR, Kuhn GA, Christen P, Hofmann S, Müller R. Tourolle Né Betts DC, et al. Among authors: wehrle e. Sci Rep. 2020 Jan 24;10(1):1100. doi: 10.1038/s41598-020-57461-5. Sci Rep. 2020. PMID: 31980656 Free PMC article.

3

Real-time finite element analysis allows homogenization of tissue scale strains and reduces variance in a mouse defect healing model.

Paul GR, Wehrle E, Tourolle DC, Kuhn GA, Müller R. Paul GR, et al. Among authors: wehrle e. Sci Rep. 2021 Jun 29;11(1):13511. doi: 10.1038/s41598-021-92961-y. Sci Rep. 2021. PMID: 34188165 Free PMC article.

4

Individualized cyclic mechanical loading improves callus properties during the remodelling phase of fracture healing in mice as assessed from time-lapsed in vivo imaging.

Wehrle E, Paul GR, Tourolle Né Betts DC, Kuhn GA, Müller R. Wehrle E, et al. Sci Rep. 2021 Nov 29;11(1):23037. doi: 10.1038/s41598-021-02368-y. Sci Rep. 2021. PMID: 34845246 Free PMC article.

5

Protocol for preparing formalin-fixed paraffin-embedded musculoskeletal tissue samples from mice for spatial transcriptomics.

Wehrle E, Günther D, Mathavan N, Singh A, Müller R. Wehrle E, et al. STAR Protoc. 2024 Jun 21;5(2):102986. doi: 10.1016/j.xpro.2024.102986. Epub 2024 Mar 29. STAR Protoc. 2024. PMID: 38555590 Free PMC article.

6

Bone mechanobiology in mice: toward single-cell in vivo mechanomics.

Scheuren A, Wehrle E, Flohr F, Müller R. Scheuren A, et al. Among authors: wehrle e. Biomech Model Mechanobiol. 2017 Dec;16(6):2017-2034. doi: 10.1007/s10237-017-0935-1. Epub 2017 Jul 22. Biomech Model Mechanobiol. 2017. PMID: 28735414

7

Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models.

Wehrle E, Tourolle Né Betts DC, Kuhn GA, Scheuren AC, Hofmann S, Müller R. Wehrle E, et al. Sci Rep. 2019 Nov 25;9(1):17445. doi: 10.1038/s41598-019-53822-x. Sci Rep. 2019. PMID: 31768003 Free PMC article.

8

Spatio-temporal characterization of fracture healing patterns and assessment of biomaterials by time-lapsed in vivo micro-computed tomography.

Wehrle E, Tourolle Né Betts DC, Kuhn GA, Floreani E, Nambiar MH, Schroeder BJ, Hofmann S, Müller R. Wehrle E, et al. Sci Rep. 2021 Apr 21;11(1):8660. doi: 10.1038/s41598-021-87788-6. Sci Rep. 2021. PMID: 33883593 Free PMC article.

9

Tissue-Level Regeneration and Remodeling Dynamics are Driven by Mechanical Stimuli in the Microenvironment in a Post-Bridging Loaded Femur Defect Healing Model in Mice.

Paul GR, Vallaster P, Rüegg M, Scheuren AC, Tourolle DC, Kuhn GA, Wehrle E, Müller R. Paul GR, et al. Among authors: wehrle e. Front Cell Dev Biol. 2022 May 24;10:856204. doi: 10.3389/fcell.2022.856204. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35686050 Free PMC article.

10

Trabecular bone remodeling in the aging mouse: A micro-multiphysics agent-based in silico model using single-cell mechanomics.

Boaretti D, Marques FC, Ledoux C, Singh A, Kendall JJ, Wehrle E, Kuhn GA, Bansod YD, Schulte FA, Müller R. Boaretti D, et al. Among authors: wehrle e. Front Bioeng Biotechnol. 2023 Mar 2;11:1091294. doi: 10.3389/fbioe.2023.1091294. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 36937760 Free PMC article.

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