Sommer R - Search Results

1

A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity.

Beshr G, Sikandar A, Gläser J, Fares M, Sommer R, Wagner S, Köhnke J, Titz A. Beshr G, et al. Among authors: sommer r. J Biol Chem. 2024 Dec 30:108151. doi: 10.1016/j.jbc.2024.108151. Online ahead of print. J Biol Chem. 2024. PMID: 39743000 Free article.

2

A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB.

Sommer R, Exner TE, Titz A. Sommer R, et al. PLoS One. 2014 Nov 21;9(11):e112822. doi: 10.1371/journal.pone.0112822. eCollection 2014. PLoS One. 2014. PMID: 25415418 Free PMC article.

3

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.

Wagner S, Sommer R, Hinsberger S, Lu C, Hartmann RW, Empting M, Titz A. Wagner S, et al. Among authors: sommer r. J Med Chem. 2016 Jul 14;59(13):5929-69. doi: 10.1021/acs.jmedchem.5b01698. Epub 2016 Feb 18. J Med Chem. 2016. PMID: 26804741

4

Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa.

Joachim I, Rikker S, Hauck D, Ponader D, Boden S, Sommer R, Hartmann L, Titz A. Joachim I, et al. Among authors: sommer r. Org Biomol Chem. 2016 Aug 16;14(33):7933-48. doi: 10.1039/c6ob01313a. Org Biomol Chem. 2016. PMID: 27488655

5

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside.

Sommer R, Hauck D, Varrot A, Imberty A, Künzler M, Titz A. Sommer R, et al. Beilstein J Org Chem. 2016 Dec 22;12:2828-2833. doi: 10.3762/bjoc.12.282. eCollection 2016. Beilstein J Org Chem. 2016. PMID: 28144356 Free PMC article.

6

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.

Wagner S, Hauck D, Hoffmann M, Sommer R, Joachim I, Müller R, Imberty A, Varrot A, Titz A. Wagner S, et al. Among authors: sommer r. Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16559-16564. doi: 10.1002/anie.201709368. Epub 2017 Nov 28. Angew Chem Int Ed Engl. 2017. PMID: 28960731 Free PMC article.

7

The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery.

Sommer R, Wagner S, Varrot A, Nycholat CM, Khaledi A, Häussler S, Paulson JC, Imberty A, Titz A. Sommer R, et al. Chem Sci. 2016 Aug 1;7(8):4990-5001. doi: 10.1039/c6sc00696e. Epub 2016 May 11. Chem Sci. 2016. PMID: 30155149 Free PMC article.

8

Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study.

Lepsik M, Sommer R, Kuhaudomlarp S, Lelimousin M, Paci E, Varrot A, Titz A, Imberty A. Lepsik M, et al. Among authors: sommer r. Eur J Med Chem. 2019 Sep 1;177:212-220. doi: 10.1016/j.ejmech.2019.05.049. Epub 2019 May 18. Eur J Med Chem. 2019. PMID: 31146126

9

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors.

Sommer R, Rox K, Wagner S, Hauck D, Henrikus SS, Newsad S, Arnold T, Ryckmans T, Brönstrup M, Imberty A, Varrot A, Hartmann RW, Titz A. Sommer R, et al. J Med Chem. 2019 Oct 24;62(20):9201-9216. doi: 10.1021/acs.jmedchem.9b01120. Epub 2019 Oct 11. J Med Chem. 2019. PMID: 31553873 Free PMC article.

10

Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa.

Hofmann A, Sommer R, Hauck D, Stifel J, Göttker-Schnetmann I, Titz A. Hofmann A, et al. Among authors: sommer r. Carbohydr Res. 2015 Aug 14;412:34-42. doi: 10.1016/j.carres.2015.04.010. Epub 2015 May 5. Carbohydr Res. 2015. PMID: 26004349

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