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Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L, Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, Yan W, Kong Y, Yang L, Wang X, Lei D, Feng X, Liu X, Yu X, Wang Y, Li Q, Shao ZH, Yang F, Sun JP. Shang P, et al. Cell. 2023 Nov 22;186(24):5347-5362.e24. doi: 10.1016/j.cell.2023.10.014. Epub 2023 Nov 13. Cell. 2023. PMID: 37963465 Free article.
Structural basis of amine odorant perception by a mammal olfactory receptor.
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP. Guo L, et al. Among authors: zhu k. Nature. 2023 Jun;618(7963):193-200. doi: 10.1038/s41586-023-06106-4. Epub 2023 May 24. Nature. 2023. PMID: 37225986
Evolutionary study and structural basis of proton sensing by Mus GPR4 and Xenopus GPR4.
Wen X, Shang P, Chen H, Guo L, Rong N, Jiang X, Li X, Liu J, Yang G, Zhang J, Zhu K, Meng Q, He X, Wang Z, Liu Z, Cheng H, Zheng Y, Zhang B, Pang J, Liu Z, Xiao P, Chen Y, Liu L, Luo F, Yu X, Yi F, Zhang P, Yang F, Deng C, Sun JP. Wen X, et al. Among authors: zhu k. Cell. 2024 Dec 31:S0092-8674(24)01380-1. doi: 10.1016/j.cell.2024.12.001. Online ahead of print. Cell. 2024. PMID: 39753131
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, Peng S, Liu Y, Wang C, Luo X, Lv Z, Kang D, Yu X, Zhang C, Jiang Y, Dong X, Zhou J, Liu Z, Yang F, Eric Xu H, Sun JP. Guo L, et al. Among authors: zhu k. Nat Commun. 2023 Aug 17;14(1):5004. doi: 10.1038/s41467-023-40705-z. Nat Commun. 2023. PMID: 37591889 Free PMC article.
6,169 results