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Biophysical and Structural Features of αβT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation.
Mallis RJ, Brazin KN, Duke-Cohan JS, Akitsu A, Stephens HM, Chang-Gonzalez AC, Masi DJ, Kirkpatrick EH, Holliday EL, Feng Y, Zienkiewicz KJ, Lee JJ, Cinella V, Uberoy KI, Tan K, Wagner G, Arthanari H, Hwang W, Lang MJ, Reinherz EL. Mallis RJ, et al. Among authors: arthanari h. Immunol Rev. 2024 Dec 29. doi: 10.1111/imr.13432. Online ahead of print. Immunol Rev. 2024. PMID: 39745432 Review.
The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Brazin KN, Mallis RJ, Boeszoermenyi A, Feng Y, Yoshizawa A, Reche PA, Kaur P, Bi K, Hussey RE, Duke-Cohan JS, Song L, Wagner G, Arthanari H, Lang MJ, Reinherz EL. Brazin KN, et al. Among authors: arthanari h. Immunity. 2018 Nov 20;49(5):829-841.e6. doi: 10.1016/j.immuni.2018.09.007. Epub 2018 Oct 30. Immunity. 2018. PMID: 30389415 Free PMC article.
Pre-T cell receptors topologically sample self-ligands during thymocyte β-selection.
Li X, Mizsei R, Tan K, Mallis RJ, Duke-Cohan JS, Akitsu A, Tetteh PW, Dubey A, Hwang W, Wagner G, Lang MJ, Arthanari H, Wang JH, Reinherz EL. Li X, et al. Among authors: arthanari h. Science. 2021 Jan 8;371(6525):181-185. doi: 10.1126/science.abe0918. Epub 2020 Dec 17. Science. 2021. PMID: 33335016 Free PMC article.
Pre-TCR ligand binding impacts thymocyte development before αβTCR expression.
Mallis RJ, Bai K, Arthanari H, Hussey RE, Handley M, Li Z, Chingozha L, Duke-Cohan JS, Lu H, Wang JH, Zhu C, Wagner G, Reinherz EL. Mallis RJ, et al. Among authors: arthanari h. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8373-8. doi: 10.1073/pnas.1504971112. Epub 2015 Jun 8. Proc Natl Acad Sci U S A. 2015. PMID: 26056289 Free PMC article.
132 results