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Biophysical and Structural Features of αβT-Cell Receptor Mechanosensing: A Paradigmatic Shift in Understanding T-Cell Activation.
Mallis RJ, Brazin KN, Duke-Cohan JS, Akitsu A, Stephens HM, Chang-Gonzalez AC, Masi DJ, Kirkpatrick EH, Holliday EL, Feng Y, Zienkiewicz KJ, Lee JJ, Cinella V, Uberoy KI, Tan K, Wagner G, Arthanari H, Hwang W, Lang MJ, Reinherz EL. Mallis RJ, et al. Among authors: feng y. Immunol Rev. 2024 Dec 29. doi: 10.1111/imr.13432. Online ahead of print. Immunol Rev. 2024. PMID: 39745432 Review.
Mechanosensing drives acuity of αβ T-cell recognition.
Feng Y, Brazin KN, Kobayashi E, Mallis RJ, Reinherz EL, Lang MJ. Feng Y, et al. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8204-E8213. doi: 10.1073/pnas.1703559114. Epub 2017 Aug 15. Proc Natl Acad Sci U S A. 2017. PMID: 28811364 Free PMC article.
The T Cell Antigen Receptor α Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Brazin KN, Mallis RJ, Boeszoermenyi A, Feng Y, Yoshizawa A, Reche PA, Kaur P, Bi K, Hussey RE, Duke-Cohan JS, Song L, Wagner G, Arthanari H, Lang MJ, Reinherz EL. Brazin KN, et al. Among authors: feng y. Immunity. 2018 Nov 20;49(5):829-841.e6. doi: 10.1016/j.immuni.2018.09.007. Epub 2018 Oct 30. Immunity. 2018. PMID: 30389415 Free PMC article.
Parsing digital or analog TCR performance through piconewton forces.
Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirkpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL. Akitsu A, et al. Among authors: feng y, feng ww. Sci Adv. 2024 Aug 16;10(33):eado4313. doi: 10.1126/sciadv.ado4313. Epub 2024 Aug 14. Sci Adv. 2024. PMID: 39141734 Free PMC article.
Parsing digital or analogue TCR performance through piconewton forces.
Akitsu A, Kobayashi E, Feng Y, Stephens HM, Brazin KN, Masi DJ, Kirpatrick EH, Mallis RJ, Duke-Cohan JS, Booker MA, Cinella V, Feng WW, Holliday EL, Lee JJ, Zienkiewicz KJ, Tolstorukov MY, Hwang W, Lang MJ, Reinherz EL. Akitsu A, et al. Among authors: feng y, feng ww. bioRxiv [Preprint]. 2023 Nov 30:2023.11.29.568292. doi: 10.1101/2023.11.29.568292. bioRxiv. 2023. Update in: Sci Adv. 2024 Aug 16;10(33):eado4313. doi: 10.1126/sciadv.ado4313 PMID: 38076892 Free PMC article. Updated. Preprint.
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