Botas J - Search Results

1

[No authors listed] [No authors listed] PMID: 39751092

2

Tau polarizes an aging transcriptional signature to excitatory neurons and glia.

Wu T, Deger JM, Ye H, Guo C, Dhindsa J, Pekarek BT, Al-Ouran R, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Wu T, et al. Among authors: botas j. Elife. 2023 May 23;12:e85251. doi: 10.7554/eLife.85251. Elife. 2023. PMID: 37219079 Free PMC article.

3

[No title available]

[No authors listed] [No authors listed] PMID: 39751595

4

Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease.

Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Chouhan AK, et al. Among authors: botas j. Acta Neuropathol Commun. 2016 Jun 23;4(1):62. doi: 10.1186/s40478-016-0333-4. Acta Neuropathol Commun. 2016. PMID: 27338814 Free PMC article.

5

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.

Kim YW, Al-Ramahi I, Koire A, Wilson SJ, Konecki DM, Mota S, Soleimani S, Botas J, Lichtarge O. Kim YW, et al. Among authors: botas j. Alzheimers Dement. 2021 May;17(5):831-846. doi: 10.1002/alz.12240. Epub 2020 Dec 7. Alzheimers Dement. 2021. PMID: 33576571 Free PMC article.

6

Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.

Onur TS, Laitman A, Zhao H, Keyho R, Kim H, Wang J, Mair M, Wang H, Li L, Perez A, de Haro M, Wan YW, Allen G, Lu B, Al-Ramahi I, Liu Z, Botas J. Onur TS, et al. Among authors: botas j. Elife. 2021 Apr 19;10:e64564. doi: 10.7554/eLife.64564. Elife. 2021. PMID: 33871358 Free PMC article.

7

Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.

Li J, Amoh BK, McCormick E, Tarkunde A, Zhu KF, Perez A, Mair M, Moore J, Shulman JM, Al-Ramahi I, Botas J. Li J, et al. Among authors: botas j. Hum Mol Genet. 2023 Jan 27;32(4):685-695. doi: 10.1093/hmg/ddac230. Hum Mol Genet. 2023. PMID: 36173927 Free PMC article.

8

Identification of risk genes for Alzheimer's disease by gene embedding.

Lagisetty Y, Bourquard T, Al-Ramahi I, Mangleburg CG, Mota S, Soleimani S, Shulman JM, Botas J, Lee K, Lichtarge O. Lagisetty Y, et al. Among authors: botas j. Cell Genom. 2022 Sep 14;2(9):100162. doi: 10.1016/j.xgen.2022.100162. Epub 2022 Jul 26. Cell Genom. 2022. PMID: 36268052 Free PMC article.

9

Evolutionarily conserved regulators of tau identify targets for new therapies.

Kim J, de Haro M, Al-Ramahi I, Garaicoechea LL, Jeong HH, Sonn JY, Tadros B, Liu Z, Botas J, Zoghbi HY. Kim J, et al. Among authors: botas j. Neuron. 2023 Mar 15;111(6):824-838.e7. doi: 10.1016/j.neuron.2022.12.012. Epub 2023 Jan 6. Neuron. 2023. PMID: 36610398 Free article.

10

Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.

Yu M, Ye H, De-Paula RB, Mangleburg CG, Wu T, Lee TV, Li Y, Duong D, Phillips B, Cruchaga C, Allen GI, Seyfried NT, Al-Ramahi I, Botas J, Shulman JM. Yu M, et al. Among authors: botas j. PLoS Genet. 2023 May 18;19(5):e1010760. doi: 10.1371/journal.pgen.1010760. eCollection 2023 May. PLoS Genet. 2023. PMID: 37200393 Free PMC article.

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