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A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia.
Dong Z, Sepulveda H, Arteaga-Vazquez LJ, Blouin C, Fernandez J, Binder M, Chou WC, Tien HF, Patnaik MM, Faulkner GJ, Myers SA, Rao A. Dong Z, et al. Among authors: tien hf. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2413302121. doi: 10.1073/pnas.2413302121. Epub 2025 Jan 3. Proc Natl Acad Sci U S A. 2025. PMID: 39752521
Acute Promyelocytic Leukemia Asian Consortium study of arsenic trioxide in newly-diagnosed patients: impact and outcome.
Gill H, Raghupathy R, Hou HA, Tsai XC, Tantiworawit A, Ooi MG, Gan GG, Wong CL, Yim RLH, Chin L, Lee P, Li VWK, Au L, Zhang Q, Leung GMK, Wu TKY, Lee YYC, Chng WJ, Tien HF, Kumana CR, Kwong YL. Gill H, et al. Among authors: tien hf. Blood Adv. 2024 Dec 18:bloodadvances.2024014999. doi: 10.1182/bloodadvances.2024014999. Online ahead of print. Blood Adv. 2024. PMID: 39693517
Synergistic effect of concurrent high molecular risk mutations and lower JAK2 mutant variant allele frequencies on prognosis in patients with myelofibrosis-insights from a multicenter study.
Wang YH, Wei CH, Lin CC, Gurnari C, Awada H, Benajiba L, Daltro de Oliveira R, Soret-Dulphy J, Cassinat B, Zucenka A, Mosquera Orgueira A, Yuan CT, Lee SH, Yao CY, Gurashi K, Hou HA, Batta K, Pérez Encinas MM, Chou WC, Maciejewski JP, Wiseman DH, Kiladjian JJ, Tien HF. Wang YH, et al. Among authors: tien hf. Leukemia. 2024 Oct 4. doi: 10.1038/s41375-024-02422-4. Online ahead of print. Leukemia. 2024. PMID: 39367172
Genetic risk classification for adults with AML receiving less-intensive therapies: the 2024 ELN recommendations.
Döhner H, DiNardo CD, Appelbaum FR, Craddock C, Dombret H, Ebert BL, Fenaux P, Godley LA, Hasserjian RP, Larson RA, Levine RL, Miyazaki Y, Niederwieser D, Ossenkoppele G, Röllig C, Sierra J, Stein EM, Tallman MS, Tien HF, Wang J, Wierzbowska A, Wei AH, Löwenberg B. Döhner H, et al. Among authors: tien hf. Blood. 2024 Nov 21;144(21):2169-2173. doi: 10.1182/blood.2024025409. Blood. 2024. PMID: 39133932
Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion.
Montoro MJ, Palomo L, Haferlach C, Acha P, Chan O, Navarro V, Kubota Y, Schulz FI, Meggendorfer M, Briski R, Al Ali N, Xicoy B, López-Cadenas F, Bosch F, González T, Eder LN, Jerez A, Wang YH, Campagna A, Santini V, Bernal Del Castillo T, Such E, Tien HF, Diaz Varela N, Platzbecker U, Haase D, Díez-Campelo M, Della Porta M, Garcia-Manero G, Wiseman DH, Germing U, Maciejewski JP, Komrokji RS, Sole F, Haferlach T, Valcárcel D. Montoro MJ, et al. Among authors: tien hf. Blood. 2024 Oct 17;144(16):1722-1731. doi: 10.1182/blood.2024023840. Blood. 2024. PMID: 39074355
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