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Page 1
Blood DNA virome associates with autoimmune diseases and COVID-19.
Sasa N, Kojima S, Koide R, Hasegawa T, Namkoong H, Hirota T, Watanabe R, Nakamura Y, Oguro-Igashira E, Ogawa K, Yata T, Sonehara K, Yamamoto K, Kishikawa T, Sakaue S, Edahiro R, Shirai Y, Maeda Y, Nii T, Chubachi S, Tanaka H, Yabukami H, Suzuki A, Nakajima K, Arase N, Okamoto T, Nishikawa R, Namba S, Naito T, Miyagawa I, Tanaka H, Ueno M, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Ikumi K, Nishida E, Nakagawa I, Yagita-Sakamaki M, Yoshimura M, Ohshima S, Kinoshita M, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Uchida A, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Saigusa M, Shirai T, Hizawa N, Nakata K; Japan COVID-19 Task Force; Imafuku S, Tada Y, Asano Y, Sato S, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Kawamura T, Shimada S, Katayama I, Poisner HM, Mack TM, Bick AG, Higasa K, Okuno T, Mochizuki H, Ishii M, Koi… See abstract for full author list ➔ Sasa N, et al. Among authors: ohkouchi s. Nat Genet. 2025 Jan;57(1):65-79. doi: 10.1038/s41588-024-02022-z. Epub 2025 Jan 3. Nat Genet. 2025. PMID: 39753770 Free PMC article.
Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis.
Sakaue S, Yamaguchi E, Inoue Y, Takahashi M, Hirata J, Suzuki K, Ito S, Arai T, Hirose M, Tanino Y, Nikaido T, Ichiwata T, Ohkouchi S, Hirano T, Takada T, Miyawaki S, Dofuku S, Maeda Y, Nii T, Kishikawa T, Ogawa K, Masuda T, Yamamoto K, Sonehara K, Tazawa R, Morimoto K, Takaki M, Konno S, Suzuki M, Tomii K, Nakagawa A, Handa T, Tanizawa K, Ishii H, Ishida M, Kato T, Takeda N, Yokomura K, Matsui T, Watanabe M, Inoue H, Imaizumi K, Goto Y, Kida H, Fujisawa T, Suda T, Yamada T, Satake Y, Ibata H, Hizawa N, Mochizuki H, Kumanogoh A, Matsuda F, Nakata K, Hirota T, Tamari M, Okada Y. Sakaue S, et al. Among authors: ohkouchi s. Nat Commun. 2021 Feb 15;12(1):1032. doi: 10.1038/s41467-021-21011-y. Nat Commun. 2021. PMID: 33589587 Free PMC article.
Quantitative Evaluation of Changes in Three-Dimensional CT Density Distributions in Pulmonary Alveolar Proteinosis after GM-CSF Inhalation.
Oda M, Yamaura K, Ishii H, Kitamura N, Tazawa R, Abe M, Tatsumi K, Eda R, Kondoh S, Morimoto K, Tanaka T, Yamaguchi E, Takahashi A, Izumi S, Sugiyama H, Nakagawa A, Tomii K, Suzuki M, Konno S, Ohkouchi S, Tode N, Handa T, Hirai T, Inoue Y, Arai T, Asakawa K, Tanaka T, Takada T, Nonaka H, Nakata K. Oda M, et al. Among authors: ohkouchi s. Respiration. 2023;102(2):101-109. doi: 10.1159/000528038. Epub 2022 Dec 9. Respiration. 2023. PMID: 36502800
Bilateral peripheral infiltrates refractory to immunosuppressants were diagnosed as autoimmune pulmonary alveolar proteinosis and improved by inhalation of granulocyte/macrophage-colony stimulating factor.
Satoh H, Tazawa R, Sakakibara T, Ohkouchi S, Ebina M, Miki M, Nakata K, Nukiwa T. Satoh H, et al. Among authors: ohkouchi s. Intern Med. 2012;51(13):1737-42. doi: 10.2169/internalmedicine.51.6093. Epub 2012 Jul 1. Intern Med. 2012. PMID: 22790136 Free article. Review.
Duration of benefit in patients with autoimmune pulmonary alveolar proteinosis after inhaled granulocyte-macrophage colony-stimulating factor therapy.
Tazawa R, Inoue Y, Arai T, Takada T, Kasahara Y, Hojo M, Ohkouchi S, Tsuchihashi Y, Yokoba M, Eda R, Nakayama H, Ishii H, Nei T, Morimoto K, Nasuhara Y, Ebina M, Akira M, Ichiwata T, Tatsumi K, Yamaguchi E, Nakata K. Tazawa R, et al. Among authors: ohkouchi s. Chest. 2014 Apr;145(4):729-737. doi: 10.1378/chest.13-0603. Chest. 2014. PMID: 24158247 Clinical Trial.
A mathematical model to predict protein wash out kinetics during whole-lung lavage in autoimmune pulmonary alveolar proteinosis.
Akasaka K, Tanaka T, Maruyama T, Kitamura N, Hashimoto A, Ito Y, Watanabe H, Wakayama T, Arai T, Hayashi M, Moriyama H, Uchida K, Ohkouchi S, Tazawa R, Takada T, Yamaguchi E, Ichiwata T, Hirose M, Arai T, Inoue Y, Kobayashi H, Nakata K. Akasaka K, et al. Among authors: ohkouchi s. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L105-17. doi: 10.1152/ajplung.00239.2014. Epub 2014 Nov 14. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25398988 Free article.
A Semiquantitative Computed Tomographic Grading System for Evaluating Therapeutic Response in Pulmonary Alveolar Proteinosis.
Tokura S, Akira M, Okuma T, Tazawa R, Arai T, Sugimoto C, Matsumuro A, Hirose M, Takada T, Nakata K, Ishii H, Kasahara Y, Hojo M, Ohkouchi S, Tsuchihashi Y, Yokoba M, Eda R, Nakayama H, Nei T, Morimoto K, Nasuhara Y, Ebina M, Ichiwata T, Tatsumi K, Yamaguchi E, Inoue Y. Tokura S, et al. Among authors: ohkouchi s. Ann Am Thorac Soc. 2017 Sep;14(9):1403-1411. doi: 10.1513/AnnalsATS.201607-574OC. Ann Am Thorac Soc. 2017. PMID: 28489417 Clinical Trial.
Inhaled GM-CSF for Pulmonary Alveolar Proteinosis.
Tazawa R, Ueda T, Abe M, Tatsumi K, Eda R, Kondoh S, Morimoto K, Tanaka T, Yamaguchi E, Takahashi A, Oda M, Ishii H, Izumi S, Sugiyama H, Nakagawa A, Tomii K, Suzuki M, Konno S, Ohkouchi S, Tode N, Handa T, Hirai T, Inoue Y, Arai T, Asakawa K, Sakagami T, Hashimoto A, Tanaka T, Takada T, Mikami A, Kitamura N, Nakata K. Tazawa R, et al. Among authors: ohkouchi s. N Engl J Med. 2019 Sep 5;381(10):923-932. doi: 10.1056/NEJMoa1816216. N Engl J Med. 2019. PMID: 31483963 Clinical Trial.
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